Evidence map›Paper›PMID 23434067›Full record

ReviewCurrent opinion in cell biology2013

Chromatin-tethered MAPKs.

Aileen M Klein, Elma Zaganjor, Melanie H Cobb

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
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  6. Review
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  8. Article
  9. The Anti-Apoptotic Role of COX-2 duringInfection and immunity · 2022
    Article
  10. Control of Gene Expression via the Yeast CWI Pathway.International journal of molecular sciences · 2022
    Review
  11. Review
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aileen M KleinDepartment of Pharmacology, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390-9041, United States.
Elma Zaganjor
Melanie H Cobb

Funding

Insulin-Regulated MAP Kinase PathwaysR37DK034128 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI COBB, MELANIE H. · 2007 to 2016
$5.1M
NIDDK NIH HHS R37 DK034128
6 · The paper itself

Abstract

Mitogen-activated protein kinases (MAPKs) are a family of protein kinases that are essential nodes in many cellular regulatory circuits including those that take place on DNA. Most members of the four MAPK subgroups that exist in canonical three kinase cascades-extracellular signal-regulated kinases 1 and 2 (ERK1/2), ERK5, c-Jun N-terminal kinases (JNK1-3), and p38 (α, β, γ, and δ) families-have been shown to perform regulatory functions on chromatin. This review offers a brief update on the variety of processes that involve MAPKs and available mechanisms garnered in the last two years.

Indexed as

AnimalsChromatinChromatin Assembly and DisassemblyDNAExtracellular Signal-Regulated MAP KinasesHumansJNK Mitogen-Activated Protein KinasesMAP Kinase Signaling SystemMitogen-Activated Protein KinasesOpen Reading FramesTranscription FactorsChromatinDNAExtracellular Signal-Regulated MAP KinasesJNK Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesTranscription Factors

Identifiers

PMID23434067
PMCPMC3654648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.