Evidence map›Paper›PMID 23432992›Full record

SynthesisAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2013

A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directions.

J P Singer, J Chen, P D Blanc, L E Leard, J Kukreja, H Chen

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05309551 (The Effects of Inspiratory Muscle Training Immediatley After Lung Transplantation), which is not on this map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05309551 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

The Effects of Inspiratory Muscle Training Immediatley After Lung Transplantation: a Randomized Controlled Trial

TypeinterventionalSponsorOhio State UniversityRan2022 to 2026Enrolled90ConditionsLung Transplantation, Chronic Lung Disease, Muscle Weakness, RehabilitationArmsIMT- Intervention group, IMT- Placebo group
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Pattern and Predictors of Hospital Readmission During the First Year After Lung Transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2017
    Trial
  5. Development and psychometric properties of the Pulmonary-specific Quality-of-Life Scale in lung transplant patients.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2015
    Trial
  6. Trial
  7. Observational
  8. Observational
  9. Observational
  10. Recovery of extracorporeal lungs using cross-circulation with injured recipient swine.The Journal of thoracic and cardiovascular surgery · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J P SingerDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA.
J ChenCardiovascular Research Institute, UC San Francisco, San Francisco, CA.
P D BlancDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA.
L E LeardDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA.
J KukrejaDivision of Cardiothoracic Surgery, UC San Francisco, CA.
H ChenGenentech Inc, San Francisco, CA.

Funding

The Effects of Lung Transplant on Disability and Health-Related Quality of LifeK23HL111115 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SINGER, JONATHAN PAUL · 2012 to 2016
$832k
Evaluating Health-related Quality-of-life in Pulmonary Arterial HypertensionK23HL086585 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHEN, HUBERT · 2007 to 2011
$762k
The effects of lung transplantation on lung disease related disabilitiesF32HL107003 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SINGER, JONATHAN PAUL · 2011 to 2011
$63k
NHLBI NIH HHS F32 HL107003NHLBI NIH HHS F32 HL107003-01NHLBI NIH HHS K23 HL086585NHLBI NIH HHS K23 HL111115
6 · The paper itself

Abstract

Health-related quality of life (HRQL) has been assessed in various lung transplantation (LT) investigations but never analyzed systematically across multiple studies. We addressed this knowledge gap through a systematic literature review. We searched the PubMed, CINAHL and PsychInfo databases for publications from January 1, 1983 to December 31, 2011. We performed a thematic analysis of published studies of HRQL in LT. Using a comparative, consensus-based approach, we identified themes that consistently emerged from the data, classifying each study according to primary and secondary thematic categories as well as by study design. Of 749 publications initially identified, 73 remained after exclusions. Seven core themes emerged: (1) Determinants of HRQL; (2) Psychosocial factors in HRQL; (3) Pre- and posttransplant HRQL comparisons; (4) Long-term longitudinal HRQL studies; (5) HRQL effects of therapies and interventions; (6) HRQL instrument validation and methodology; (7) HRQL prediction of clinical outcomes. Overall, LT significantly and substantially improves HRQL, predominantly in domains related to physical health and functioning. The existing literature demonstrates substantial heterogeneity in methodology and approach; relatively few studies assessed HRQL longitudinally within the same persons. Opportunity for future study lies in validating existing and potential novel HRQL instruments and further elucidating the determinants of HRQL through longitudinal multidimensional investigation.

Indexed as

Outcome Assessment, Health CareQuality of LifeDecision MakingHumansLung DiseasesLung TransplantationPostoperative ComplicationsSocial SupportSurveys and QuestionnairesTreatment Outcome

Identifiers

PMID23432992
PMCPMC3622720

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.