ArticleBMC genomics2013
Comparative transcriptomics reveals different strategies of Trichoderma mycoparasitism.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers.
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Who cites it
115 citing papers in PubMed, 305 citations in OpenAlex.
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- Mechanisms of Trichoderma-Mediated Plant Growth Promotion: From Metabolites to Plant Responses.Plants (Basel, Switzerland) · 2026Review
- Effects of Fermentation Broth from the Biocontrol FungusMicroorganisms · 2026Article
- Pathogenicity of Cadophora luteo-olivacea on Quercus robur and multi-omics characterization of antagonism by Trichoderma atroviride.Scientific reports · 2026Article
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- TrichoBase: a standardized genomic resource for comparative genomics of Trichoderma species.BMC genomic data · 2026Article
- Applicability of Trichoderma spp. in sustainable agriculture against fungal and nematode phytopathogens: a review.Folia microbiologica · 2026Review
- Structural insights into cellobiose dehydrogenases of a non-lignocellulolytic fungus and their transcriptional dynamics across different nutritional modes.Microbiology spectrum · 2026Article
- Biocontrol potential of phyllosphere fungi from diseased leaves against Colletotrichum gloeosporioides and Pseudocryphonectria elaeocarpicola.Archives of microbiology · 2026Article
- More diverse than previously thought: a novelIMA fungus · 2026Article
- In-vitro evaluation of selected nativeFrontiers in microbiology · 2026Article
- Review
- Novel peptaibiotics identified from Trichoderma clade Viride.Natural products and bioprospecting · 2025Article
- Biocontrol Potential of NativeJournal of fungi (Basel, Switzerland) · 2025Article
- Multi-omics analysis of Trichoderma reesei mutant with high glucanase activity.Scientific reports · 2025Article
- Linking a polyketide synthase gene cluster to 6-pentyl-alpha-pyrone, a Trichoderma metabolite with diverse bioactivities.Microbial cell factories · 2025Article
- Applications of endophytic fungi in plant disease control.Archives of microbiology · 2025Review
- Dual RNA-seq reveals transcriptome changes during Fusarium virguliforme-Trichoderma afroharzianum interactions.PloS one · 2025Article
- Carbon and Nitrogen Sources Influence Parasitic Responsiveness inJournal of fungi (Basel, Switzerland) · 2024Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTrichoderma is a genus of mycotrophic filamentous fungi (teleomorph Hypocrea) which possess a bright variety of biotrophic and saprotrophic lifestyles. The ability to parasitize and/or kill other fungi (mycoparasitism) is used in plant protection against soil-borne fungal diseases (biological control, or biocontrol). To investigate mechanisms of mycoparasitism, we compared the transcriptional responses of cosmopolitan opportunistic species and powerful biocontrol agents Trichoderma atroviride and T. virens with tropical ecologically restricted species T. reesei during confrontations with a plant pathogenic fungus Rhizoctonia solani.
resultsThe three Trichoderma spp. exhibited a strikingly different transcriptomic response already before physical contact with alien hyphae. T. atroviride expressed an array of genes involved in production of secondary metabolites, GH16 ß-glucanases, various proteases and small secreted cysteine rich proteins. T. virens, on the other hand, expressed mainly the genes for biosynthesis of gliotoxin, respective precursors and also glutathione, which is necessary for gliotoxin biosynthesis. In contrast, T. reesei increased the expression of genes encoding cellulases and hemicellulases, and of the genes involved in solute transport. The majority of differentially regulated genes were orthologues present in all three species or both in T. atroviride and T. virens, indicating that the regulation of expression of these genes is different in the three Trichoderma spp. The genes expressed in all three fungi exhibited a nonrandom genomic distribution, indicating a possibility for their regulation via chromatin modification.
conclusionThis genome-wide expression study demonstrates that the initial Trichoderma mycotrophy has differentiated into several alternative ecological strategies ranging from parasitism to predation and saprotrophy. It provides first insights into the mechanisms of interactions between Trichoderma and other fungi that may be exploited for further development of biofungicides.
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