Evidence map›Paper›PMID 23432522›Full record

ArticleChild development

Genetic moderation of early child-care effects on social functioning across childhood: a developmental analysis.

Jay Belsky, Michael Pluess

Abstract read
In one paragraph

Article in Child development. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Interplay between children's biobehavioral plasticity and interparental relationship in the origins of internalizing problems.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2017
    Article
  7. Article
  8. Article
  9. Oppositional defiant disorder: current insight.Psychology research and behavior management · 2017
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Differential Susceptibility of the Developing Brain to Contextual Adversity and Stress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2016
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jay BelskyHuman and Community Development, University of California, Davis, CA 95616, USA. jbelsky@ucdavis.edu
Michael Pluess

Funding

THE NICHD STUDY OF EARLY CHILD CARE--PHASE IIIU10HD025420 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CAMPBELL, SUSAN B · 1990 to 2007
$4.6M
NICHD NIH HHS U10 HD025420NICHD NIH HHS U10-HD25420
6 · The paper itself

Abstract

Data from 508 Caucasian children in the NICHD Study of Early Child Care and Youth Development shows that the DRD4 (but not 5-HTTLPR) polymorphism moderates the effect of child-care quality (but not quantity or type) on caregiver-reported externalizing problems at 54 months and in kindergarten and teacher-reported social skills at kindergarten and first grade-but not thereafter. Only children carrying the 7-repeat allele proved susceptible to quality-of-care effects. The behavior-problem interactions proved more consistent with diathesis-stress than differential-susceptibility thinking, whereas the reverse was true of the social-skills' results. Finally, the discerned Gene × Environment interactions did not account for previously reported parallel ones involving difficult temperament in infancy.

Indexed as

AdolescentChildChild Behavior DisordersChild CareChild, PreschoolFemaleGenotypeHumansInfantInterpersonal RelationsMaleParentingPolymorphism, GeneticReceptors, Dopamine D4Serotonin Plasma Membrane Transport ProteinsSocial AdjustmentDRD4 protein, humanReceptors, Dopamine D4Serotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

PMID23432522
PMCPMC4374568

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.