ArticleJournal of the American Chemical Society2013
Patchy supramolecules as versatile tools to probe hydrophobicity in nanoglobular systems.
Article in Journal of the American Chemical Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Self-Assembly of Modular Bis-MPA Dendrons into Colloidal Particles with Tunable Morphology and Selective Cytotoxicity.Nanomaterials (Basel, Switzerland) · 2026Article
- Guanosine-Based Supramolecular Particles for Enhanced Drug and Gene Delivery in Cell Culture.ACS applied bio materials · 2025Article
- Quantifying and Modulating Protein Encapsulation in Guanosine-Based Supramolecular Particles.Bioconjugate chemistry · 2023Article
- Optimizing the Production of gp145, an HIV-1 Envelope Glycoprotein Vaccine Candidate and Its Encapsulation in Guanosine Microparticles.Vaccines · 2023Article
- Screening and Quantification of the Encapsulation of Dyes in Supramolecular Particles.Langmuir : the ACS journal of surfaces and colloids · 2021Article
- Construction of Supramolecular Organogel with Circularly Polarized Luminescence by Self-Assembled Guanosine Octamer.Cell reports. Physical science · 2020Article
- Tuning thermoresponsive supramolecular G-quadruplexes.Langmuir : the ACS journal of surfaces and colloids · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
We describe precise supramolecules that enable the evaluation of the effective hydrophobicity of amphiphilic or "patchy" nanoglobular systems. These supramolecules exhibit the lower critical solution temperature phenomenon, which provides a quantitative measure of their effective hydrophobicity. Specifically, two isomeric 8-aryl-2'-deoxyguanosine derivatives with a transposed pair of methylene groups self-assemble into hexadecameric nanoglobular supramolecular G-quadruplexes (SGQs) that show large differences in their transition temperatures as determined by turbidity and differential scanning calorimetry studies. Molecular modeling studies suggested that differential clustering of the hydrophobic patches on the surface is responsible for the striking differences between the two isomeric supramolecules.
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Registered trials
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