ArticlePulmonary medicine2013
Responsiveness of Various Exercise-Testing Protocols to Therapeutic Interventions in COPD.
Article in Pulmonary medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Fixed-intensity exercise tests to measure exertional dyspnoea in chronic heart and lung populations: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Intensity of physical exercise and its effect on functional capacity in COPD: systematic review and meta-analysis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaPooled it
- Activin Type II Receptor Blockade for Treatment of Muscle Depletion in Chronic Obstructive Pulmonary Disease. A Randomized Trial.American journal of respiratory and critical care medicine · 2019Trial
- Effects of combined tiotropium/olodaterol on inspiratory capacity and exercise endurance in COPD.The European respiratory journal · 2017Trial
- Evaluation of the effects of olodaterol on exercise endurance in patients with chronic obstructive pulmonary disease: results from two 6-week crossover studies.Respiratory research · 2016Trial
- Three-minute constant rate step test for detecting exertional dyspnea relief after bronchodilation in COPD.International journal of chronic obstructive pulmonary disease · 2016Trial
- Trial
- Effect of 12 weeks of once-daily tiotropium/olodaterol on exercise endurance during constant work-rate cycling and endurance shuttle walking in chronic obstructive pulmonary disease.Therapeutic advances in respiratory diseaseTrial
- Comparative measurement properties of constant work rate cycling and the endurance shuttle walking test in COPD: the TORRACTOTherapeutic advances in respiratory diseaseTrial
- Reliability and Responsiveness of Endurance Shuttle Walk Test to Estimate Functional Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis.Oman medical journal · 2023Article
- A Conceptual Framework for Use of Increased Endurance Time During Constant Work Rate Cycle Ergometry as a Patient-Focused Meaningful Outcome in COPD Clinical Trials.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2022Review
- The use of menthol for breathlessness: a hot topic full of fresh ideas.ERJ open research · 2022Article
- Short-term effects of menthol on walking dyspnoea in patients with COPD: a randomised, single blinded, cross-over study.ERJ open research · 2021Article
- Pulmonary function testing in COPD: looking beyond the curtain of FEV1.NPJ primary care respiratory medicine · 2021Review
- High-intensity interval training accelerates oxygen uptake kinetics and improves exercise tolerance for individuals with cystic fibrosis.BMC sports science, medicine & rehabilitation · 2020Article
- Improvement In Self-Reported Physical Functioning With Tiotropium/Olodaterol In Central And Eastern European COPD Patients.International journal of chronic obstructive pulmonary disease · 2019Observational
- Effects of high intensity interval training on exercise capacity in people with cystic fibrosis: study protocol for a randomised controlled trial.BMC sports science, medicine & rehabilitation · 2018Article
- Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing.European respiratory review : an official journal of the European Respiratory Society · 2016Review
- Ambulatory Oxygen for Exercise-Induced Desaturation and Dyspnea in Chronic Obstructive Pulmonary Disease (COPD): Systematic Review and Meta-Analysis.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2016Article
- Diagnosis, assessment, and phenotyping of COPD: beyond FEV₁.International journal of chronic obstructive pulmonary disease · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise intolerance is a key element in the pathophysiology and course of Chronic Obstructive Pulmonary Disease (COPD). As such, evaluating exercise tolerance has become an important part of the management of COPD. A wide variety of exercise-testing protocols is currently available, each protocol having its own strengths and weaknesses relative to their discriminative, methodological, and evaluative characteristics. This paper aims to review the responsiveness of several exercise-testing protocols used to evaluate the efficacy of pharmacological and nonpharmacological interventions to improve exercise tolerance in COPD. This will be done taking into account the minimally important difference, an important concept in the interpretation of the findings about responsiveness of exercise testing protocols. Among the currently available exercise-testing protocols (incremental, constant work rate, or self-paced), constant work rate exercise tests (cycle endurance test and endurance shuttle walking test) emerge as the most responsive ones for detecting and quantifying changes in exercise capacity after an intervention in COPD.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.