ArticleComputational and mathematical methods in medicine2012
Numerical study for blood flow in pulmonary arteries after repair of tetralogy of Fallot.
Article in Computational and mathematical methods in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 32 citations in OpenAlex.
- Quantitative comparisons of pulmonary artery hemodynamics before and after Pulsta valve implantation in patients with Tetralogy of Fallot using computational fluid dynamics.Frontiers in cardiovascular medicine · 2025Article
- Morphometrics predicts the differential regurgitant fraction in bilateral pulmonary arteries of patients with repaired tetralogy of fallot.The international journal of cardiovascular imaging · 2024Article
- A Fluid-Structure Interaction Analysis of Blood Clot Motion in a Branch of Pulmonary Arteries.Cardiovascular engineering and technology · 2023Article
- Branch Pulmonary Artery Regurgitation in Repaired Tetralogy of Fallot: Correlation with Pulmonary Artery Morphology, Distensibility, and Right Ventricular Function.Tomography (Ann Arbor, Mich.) · 2021Article
- Characterization of Flow Dynamics in the Pulmonary Bifurcation of Patients With Repaired Tetralogy of Fallot: A Computational Approach.Frontiers in cardiovascular medicine · 2021Article
- Computational Analysis of the Pulmonary Arteries in Congenital Heart Disease: A Review of the Methods and Results.Computational and mathematical methods in medicine · 2021Review
- Numerical simulation of particle transport and deposition in the pulmonary vasculature.Journal of biomechanical engineering · 2014Article
- Quantification of pulmonary regurgitation in patients with repaired Tetralogy of Fallot by 2D phase-contrast MRI: Differences between the standard method of velocity averaging and a pixel-wise analysis.JRSM cardiovascular diseaseArticle
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pulmonary regurgitation (PR) is a common phenomenon in pulmonary arteries in patients after repair of tetralogy of Fallot (TOF). The regurgitation fraction of left pulmonary artery (LPA) is usually greater than right pulmonary artery (RPA) according to clinic data. It may be related to blood flow in pulmonary arteries. Therefore, understanding hemodynamics in pulmonary arteries helps to comprehend the reason. The aim of this study is to use 3D reconstructed pulmonary artery models from magnetic resonance imaging (MRI) and to use numerical approaches for simulation of flow variations in pulmonary arteries after repair of TOF. From the numerical results, the blood flow is influenced by the bifurcation angles and geometry of pulmonary artery. The regurgitation happens first in LPA after repair of TOF due to the small angle between LPA and main pulmonary artery (MPA). The recirculation region which obstructs forward blood flow to the left lung is found in LPA during acceleration of systole. We also analyze the pressure distribution; the extreme pressure variations are in dilation area of MPA. Numerical data including regurgitation in MPA, LPA, and RPA are compared with phase contrast MR measured data. Good agreements are found between numerical results and measured data.
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