Evidence map›Paper›PMID 23431299›Full record

ArticleJournal of oncology2013

The use of strontium-90 Beta radiotherapy as adjuvant treatment for conjunctival melanoma.

Victoria M L Cohen, Vasilios P Papastefanou, S Liu, Ian Stoker, John L Hungerford

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Yttrium-90 (American journal of ophthalmology case reports · 2024
    Article
  4. Article
  5. Article
  6. Annulus-shaped I-125 plaque brachytherapy for conjunctival melanoma.American journal of ophthalmology case reports · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Proton radiotherapy in advanced malignant melanoma of the conjunctiva.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  13. Effect of Beta Particles Spectrum on Absorbed Fraction in Internal Radiotherapy.Asia Oceania journal of nuclear medicine & biology · 2019
    Article
  14. [Adjuvant therapy and interdisciplinary follow-up care of conjunctival melanoma].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2015
    Review
  15. Article
  16. High-Dose-Rate Yttrium-90 (Ophthalmology science
    Article
  17. Article
  18. Review
  19. Innovations in brachytherapy.Taiwan journal of ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Victoria M L CohenOcular Oncology Service, St Bartholomew's Hospital and Moorfields Eye Hospital, West Smithfield, London EC1A 7BE, UK.
Vasilios P Papastefanou
S Liu
Ian Stoker
John L Hungerford
Moorfields Eye Hospital · GBUniversity College London · GBSt Bartholomew's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims. To report the safety and efficacy of strontium (Sr(90)) beta radiotherapy as adjuvant treatment for conjunctival melanoma. Methods. A retrospective cohort study was undertaken from 1999 to 2007 of all patients who underwent Sr(90) beta radiotherapy for incompletely excised conjunctival melanoma. Failure of treatment was defined as recurrence of a conjunctival melanoma at the same location following beta radiotherapy. Results. Twenty patients underwent Sr(90) beta radiotherapy for incompletely excised conjunctival melanoma. Median follow-up interval was 59 months (8-152). All patients had conjunctival melanoma involving the bulbar conjunctiva. Underlying diagnoses included PAM with atypia in 60% (12 of 20), PAM without atypia in 15% (3 of 20), and de novo conjunctival melanoma in 25% (5 of 20). Following Sr(90) beta radiotherapy, in 90% (18 out of 20) local control was achieved and visual acuity was not affected in any patient. Three patients (15%) had dry eye symptoms, episcleritis, and descemetcoele, respectively. No cataract or secondary glaucoma was reported. Conclusions. Sr(90) treatment is a very effective adjuvant treatment after excisional biopsy and cryotherapy for conjunctival melanoma with a local success rate of 90%. The treatment is not associated with significant side effects and visual acuity is not affected.

Identifiers

PMID23431299
PMCPMC3572694
OpenAlexW2054558943

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.