ArticleSarcoma2013
Surgery and actinomycin improve survival in malignant rhabdoid tumor.
Article in Sarcoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Rhabdoid Tumor Predisposition Syndrome : A Comprehensive Review of Genetics, Clinical Manifestations, and Management.Journal of Korean Neurosurgical Society · 2025Article
- Undifferentiated Rhabdoid Carcinoma of the Gastrointestinal Tract: A Rare and Aggressive Malignancy.Cureus · 2025Article
- Rhabdoid tumor predisposition syndrome: A historical review of treatments and outcomes for associated pediatric malignancies.Pediatric blood & cancer · 2024Review
- Article
- Non-Wilms' renal tumors in children: experience with 139 cases treated at a single center.BMC urology · 2022Article
- Esophageal Rhabdoid-Like Tumor: A Rare Disease With Aggressive Clinical Behavior.Frontiers in surgery · 2020Article
- Malignant rhabdoid tumor in a solitary kidney arising in an adult patient with chronic obstructive renal calculi.International journal of surgery case reports · 2019Article
- Treatment of malignant rhabdoid tumors of the head and neck with combined chemotherapy andPediatric investigation · 2018Article
- Extraordinary disease-free survival in a rare malignant extrarenal rhabdoid tumor: a case report and review of the literature.Journal of medical case reports · 2018Review
- A primary extradural malignant rhabdoid tumor at the craniovertebral junction in a 3-year-old boy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Prognostic factors and survival in non-central nervous system rhabdoid tumors.Journal of pediatric surgery · 2017Article
- Extra-cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience.Cancer research and treatment · 2015Article
- Malignant rhabdoid tumor of the small intestine in adults: a brief review of the literature and report of a case.Surgery today · 2015Review
- A Rare Case of Undifferentiated Carcinoma of the Colon with Rhabdoid Features: A Case Report and Review of the Literature.Case reports in oncological medicine · 2015Article
- Pure malignant rhabdoid tumour of the bladder.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2014Article
- Extrarenal Extracranial Rhabdoid Tumor of the Pelvis in a Young Adult-management of a Challenging Case.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric OncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose. Malignant rhabdoid tumor (MRT) is an uncommon tumor that rarely occurs outside of renal and central nervous system (CNS) sites. Data from the literature were compiled to determine prognostic factors, including both demographic and treatment variables of malignant rhabdoid tumor, focusing on those tumors arising in extra-renal, extra-CNS (ER/EC MRT) sites. Patients and Methods. A systematic review and meta-analysis was performed by extracting demographic, treatment, and survival follow up on 167 cases of primary ER/EC MRT identified in the literature. Results. No survival differences were observed between those treated with or without radiation, or with or without chemotherapy. A Cox regression of overall survival revealed several independent prognostic factors. Surgical excision had a 74% (P = 0.0003) improvement in survival. Actinomycin had a 73% (P = 0.093) improvement in survival. Older age was associated with improved survival. The four-year survival, by Kaplan-Meier estimates, comparing patients less than two years old versus older than two at diagnosis was 11% versus 35%, respectively (P = 0.0001, Log-Rank). Conclusion. ER/EC MRT is a rare, soft-tissue tumor with a poor prognosis most commonly occurring in children. Surgical resection, treatment with actinomycin, and older age at diagnosis are all associated with improved survival.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.