ArticleProceedings of the National Academy of Sciences of the United States of America2013
Proteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillata.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 96 papers.
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Who cites it
96 citing papers in PubMed.
- Coral growth, retraction, defense, and regenerative strategies revealed by live microCT.Science advances · 2026Article
- A Matter of Degrees: Latitudinal Variation in the Transcriptional Response to High and Low Temperatures in an Estuarine Cnidarian.bioRxiv : the preprint server for biology · 2026Article
- Evolutionary rewiring of the endomesoderm gene regulatory networks specify skeleton secreting cells in stony corals.bioRxiv : the preprint server for biology · 2026Article
- Building like a Coral-Parallelized, Multiscale Biofabrication.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Spatially resolved gene expression analysis illuminates location-specific functions in the reef-building coral Pocillopora acuta.PloS one · 2026Article
- Coral larval proteomics at onset of metamorphosis highlights innate immunity maturation in parallel to neuro-sensing and skeletal development.Frontiers in physiology · 2026Article
- Insights on the intracellular trafficking of calcifying medium in a reef-building coral.Communications biology · 2025Article
- Integrative analysis of coral plasticity and adaptations reveals key proteins driving resilience to changes in ocean carbonate chemistry.Marine life science & technology · 2025Article
- Thermal and Acidification Gradients Reveal Tolerance Thresholds in Pocillopora acuta Recruits.Molecular ecology · 2025Article
- Article
- Comparative genomics of two closely related Acropora coral species with different spawning seasons reveals genomic regions possibly associated with gametogenesis.BMC ecology and evolution · 2025Article
- Multidecadal decoupling between coral calcifying fluid and seawater saturation states.Science advances · 2025Article
- Changes in host gene expression patterns underpin responses of the coral Stylophora pistillata to nutrient stress.Scientific reports · 2025Article
- In-depth single-cell transcriptomic exploration of the regenerative dynamics in stony coral.Communications biology · 2025Article
- The molecular basis of octocoral calcification revealed by genome and skeletal proteome analyses.GigaScience · 2025Article
- Extreme Environmental Variability Induces Frontloading of Coral Biomineralisation Genes to Maintain Calcification Under pCOMolecular ecology · 2025Article
- How Significant Are Marine Invertebrate Collagens? Exploring Trends in Research and Innovation.Marine drugs · 2024Review
- Proteomic characterization of a foraminiferal test's organic matrix.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome ofProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome and tissue-specific transcriptomes of the large-polyp coral, Fimbriaphyllia (Euphyllia) ancora: a recipe for a coral polyp.Communications biology · 2024Article
36 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has long been recognized that a suite of proteins exists in coral skeletons that is critical for the oriented precipitation of calcium carbonate crystals, yet these proteins remain poorly characterized. Using liquid chromatography-tandem mass spectrometry analysis of proteins extracted from the cell-free skeleton of the hermatypic coral, Stylophora pistillata, combined with a draft genome assembly from the cnidarian host cells of the same species, we identified 36 coral skeletal organic matrix proteins. The proteome of the coral skeleton contains an assemblage of adhesion and structural proteins as well as two highly acidic proteins that may constitute a unique coral skeletal organic matrix protein subfamily. We compared the 36 skeletal organic matrix protein sequences to genome and transcriptome data from three other corals, three additional invertebrates, one vertebrate, and three single-celled organisms. This work represents a unique extensive proteomic analysis of biomineralization-related proteins in corals from which we identify a biomineralization "toolkit," an organic scaffold upon which aragonite crystals can be deposited in specific orientations to form a phenotypically identifiable structure.
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