GuidelineHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2012
Renal artery denervation for treating resistant hypertension : definition of the disease, patient selection and description of the procedure.
Guideline in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 9 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 9 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Systematic Review Article: New Drug Strategies for Treating Resistant Hypertension-the Importance of a Mechanistic, Personalized Approach.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Pooled it
- Personalised Single-Pill Combination Therapy in Hypertensive Patients: An Update of a Practical Treatment Platform.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017Guideline
- Clinical management of primary aldosteronism: 2013 Practical Recommendations of the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Guideline
- Clinical management of drug-induced hypertension: 2013 Practical Recommendations of the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Guideline
- Clinical management of renovascular hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Echocardiography in hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of resistant hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of hypertension in pregnancy. Practical recommendations from the Italian Society of Hypertension (SIIA). [corrected].High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of coronary heart disease in hypertension : practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Interventional Treatment of Arterial Hypertension in The Modern Era: An Updated Review from the Young Investigator Group of the European Society of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Review
- Cost-Effectiveness and Budget Impact Analysis of Radiofrequency Renal Denervation for Uncontrolled and Resistant Hypertension in Italy.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Blood Pressure Control and Clinical Outcomes After Renal Denervation Through Irrigated Catheter Radiofrequency Ablation in Patients with Resistant Hypertension: A Case Series with Up to 10 Years of Follow-Up.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Article
- Italian Society of Arterial Hypertension (SIIA) Position Paper on the Role of Renal Denervation in the Management of the Difficult-to-Treat Hypertensive Patient.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Review
- Prevalence and control of hypertension in the general practice in Italy: updated analysis of a large database.Journal of human hypertension · 2017Article
- Resistant Hypertension: An Incurable Disease or Just a Challenge For Our Medical Skill?High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2016Review
- Clinical management of patients with hypertension and high cardiovascular risk: main results of an Italian survey on blood pressure control.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Observational
- National survey on excellence centers and reference centers for hypertension diagnosis and treatment: geographical distribution, medical facilities and diagnostic opportunities.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Article
Corrections and comments
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Authors and funding
17 authors at 13 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arterial hypertension is responsible for a significant burden of cardiovascular morbidity and mortality, worldwide. Although several rational and integrated pharmacological strategies are available, the control of high blood pressure still remains largely unsatisfactory. Failure to achieve effective blood pressure control in treated hypertensive patients may have a substantial impact on individual global cardiovascular risk, since it significantly increases the risk of developing hypertension-related macrovascular and microvascular complications. Arterial hypertension is arbitrarily defined as 'resistant' or 'refractory' when the recommended blood pressure goals (clinic blood pressure below 140/90 mmHg or below 130/80 mmHg in patients with type 2 diabetes mellitus or nephropathy) are not achieved in the presence of a therapeutic strategy that includes lifestyle changes and at least three classes of antihypertensive drugs, including a diuretic, at adequate doses. Recently, an innovative non-pharmacological option has become available for treating resistant hypertension. Sympathetic denervation of renal arteries is a minimally invasive procedure that is performed via percutaneous access from the femoral artery. It consists of radiofrequency ablation of the afferent and efferent nerves of the renal sympathetic nervous system, with consequent isolation of renal parenchymal and juxtaglomerular structures from abnormal stimulation of the efferent adrenergic system. The present position paper of the Italian Society of Hypertension (SIIA) offers a diagnostic and therapeutic approach for the proper identification and effective clinical management of patients with resistant hypertension, who are candidates for renal artery denervation. These indications may have important implications not only from a clinical point of view, but also from an economic point of view, since a proper identification of patients with true resistant hypertension and an accurate selection of patients suitable for the procedure of renal denervation can contribute to an improved control of blood pressure, and thus a reduced risk of cardiovascular and cerebrovascular complications in these patients.
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