Evidence map›Paper›PMID 23430648›Full record

ReviewScience (New York, N.Y.)2013

How cells know where they are.

Arthur D Lander

Abstract readReview
In one paragraph

Review in Science (New York, N.Y.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Memoryless chemotaxis with discrete cues.Journal of the Royal Society, Interface · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Frontiers in molecular biosciences · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Arthur D LanderDepartment of Developmental and Cell Biology, and Center for Complex Biological Systems, University of California Irvine, Irvine, CA 92697, USA. adlander@uci.edu

Funding

Uncover Strategies Used By Biological SystemsP50GM076516 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LANDER, ARTHUR D · 2007 to 2016
$25.1M
Principles of Robust Developmental PatterningR01GM067247 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LANDER, ARTHUR D, NIE, QING · 2002 to 2014
$4.7M
NIGMS NIH HHS P50 GM076516NIGMS NIH HHS P50GM076516NIGMS NIH HHS R01 GM067247NIGMS NIH HHS R01GM067247
6 · The paper itself

Abstract

Development, regeneration, and even day-to-day physiology require plant and animal cells to make decisions based on their locations. The principles by which cells may do this are deceptively straightforward. But when reliability needs to be high--as often occurs during development--successful strategies tend to be anything but simple. Increasingly, the challenge facing biologists is to relate the diverse diffusible molecules, control circuits, and gene regulatory networks that help cells know where they are to the varied, sometimes stringent, constraints imposed by the need for real-world precision and accuracy.

Indexed as

Cell Physiological PhenomenaMorphogenesisAnimalsDiffusionEmbryonic DevelopmentGene Regulatory NetworksIntercellular Signaling Peptides and ProteinsSignal TransductionIntercellular Signaling Peptides and Proteins

Identifiers

PMID23430648
PMCPMC3932337

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.