ArticleEndocrine2013
Epicardial fat thickness and left ventricular mass in subjects with adrenal incidentaloma.
Article in Endocrine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nonfunctional adrenal adenomas and impaired glucose metabolism: a systematic review and meta-analysis.Endocrine · 2021Pooled it
- Cardiovascular effects of metyrapone treatment in patients with mild autonomous cortisol secretion: a secondary analysis.The Journal of clinical endocrinology and metabolism · 2026Article
- Adverse cardio-metabolic risk profile and epicardial adiposity in patients with adrenal adenoma: a cross-sectional study.Frontiers in endocrinology · 2026Article
- Silent risk of ascending artery dilatation in non-functional adrenal incidentaloma.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Clinical and Metabolic Characteristics and Follow-Up Results of Adrenal Incidentalomas: A 10-Year Experience.Cureus · 2024Article
- Epicardial and pericoronary adipose tissue and coronary plaque burden in patients with Cushing's syndrome: a propensity score-matched study.Journal of endocrinological investigation · 2024Article
- Endocrine Disorders and Peripheral Arterial Disease - A Series of Reviews Cushing Syndrome-Cortisol Excess.Current vascular pharmacology · 2024Review
- Metabolic syndrome and Visceral Adiposity Index in non-functional adrenal adenomas.Archives of endocrinology and metabolism · 2023Article
- Epicardial Fat Volume, Cardiac Function, and Incident Heart Failure: The Rotterdam Study.Journal of the American Heart Association · 2023Article
- Low catestatin as a risk factor for cardiovascular disease - assessment in patients with adrenal incidentalomas.Frontiers in endocrinology · 2023Article
- Cardiac Hypertrophy and Related Dysfunctions in Cushing Syndrome Patients-Literature Review.Journal of clinical medicine · 2022Review
- Assessment of subclinical cardiovascular alterations in nonfunctioning adrenal incidentalomas.Turkish journal of medical sciences · 2022Article
- Frequently asked questions and answers (if any) in patients with adrenal incidentaloma.Journal of endocrinological investigation · 2021Review
- Markers of Subclinical Cardiovascular Disease in Patients with Adrenal Incidentaloma.Medicina (Kaunas, Lithuania) · 2020Review
- Adrenal incidentaloma: cardiovascular and metabolic effects of mild cortisol excess.Gland surgery · 2020Review
- Nonfunctioning Adrenal Incidentalomas: The Search for Subclinical Cardiac Alterations.Arquivos brasileiros de cardiologia · 2018Article
- Assessment of Subclinical Cardiac Alterations and Atrial Electromechanical Delay by Tissue Doppler Echocardiography in Patients with Nonfunctioning Adrenal Incidentaloma.Arquivos brasileiros de cardiologia · 2018Article
- Comparison of echocardiographic findings in patients with nonfunctioning adrenal incidentalomas.The Kaohsiung journal of medical sciences · 2017Article
- Molecular Recognition in Mitochondrial Cytochromes P450 That Catalyze the Terminal Steps of Corticosteroid Biosynthesis.Biochemistry · 2017Article
- The Relationship Between Increased Epicardial Fat Thickness and Left Ventricular Hypertrophy and Carotid Intima-Media Thickness in Patients With Nonfunctional Adrenal Incidentaloma.International journal of endocrinology and metabolism · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidences indicate that patients diagnosed with adrenal incidentaloma may present with cardiovascular complications. Epicardial fat is known to play a role in left ventricle (LV) changes. Whether epicardial fat can be associated with LV mass (LVM) in patients with incidentaloma is unknown. We test the hypothesis that echocardiographic epicardial fat thickness is independently related to LVM in a well-studied group of subjects with adrenal incidentaloma. 46 consecutive patients (age 59 ± 9 years) with imaging diagnosis of adrenal incidentaloma and 30 healthy controls underwent echocardiogram for epicardial fat thickness and LVM measurement. Non-functional incidentaloma was confirmed in 40 subjects, whereas 6 patients were actually diagnosed with mild Cushing's syndrome. Epicardial fat thickness was significantly higher in patients with incidentaloma and mild Cushing's syndrome when compared to controls, (p < 0.01 for both). LVM(h2.7) was higher in subjects with adrenal incidentaloma than in controls and higher in subjects with mild Cushing's syndrome than in those with adrenal incidentaloma (p < 0.05 and p < 0.01). Multiple regression analysis showed that epicardial fat thickness was the best correlate (R (2) = 0.36, β 2.8, p < 0.01) of LVM in overall study patients. We showed for the first time that (1) epicardial fat thickness and LVM are higher in subjects with adrenal incidentaloma and (2) epicardial fat thickness independently correlates with LVM. Echocardiographic epicardial fat may serve as non-invasive marker of visceral fat and earlier cardiac abnormalities in patients with adrenal incidentaloma.
Indexed as
Identifiers
23430367What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.