ReviewMedical & biological engineering & computing2013
Understanding the mechanisms amenable to CRT response: from pre-operative multimodal image data to patient-specific computational models.
Review in Medical & biological engineering & computing, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Linking statistical shape models and simulated function in the healthy adult human heart.PLoS computational biology · 2021Article
- Patient-specific heart simulation can identify non-responders to cardiac resynchronization therapy.Heart and vessels · 2020Article
- Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium.Journal of biomechanics · 2020Article
- An Introductory Overview of Image-Based Computational Modeling in Personalized Cardiovascular Medicine.Frontiers in bioengineering and biotechnology · 2020Review
- A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.PloS one · 2020Article
- A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data.Medical image analysis · 2019Article
- Computational Modeling for Cardiac Resynchronization Therapy.Journal of cardiovascular translational research · 2018Review
- Quantitative Analysis of Electro-Anatomical Maps: Application to an Experimental Model of Left Bundle Branch Block/Cardiac Resynchronization Therapy.IEEE journal of translational engineering in health and medicine · 2017Article
- Personalized Computer Simulation of Diastolic Function in Heart Failure.Genomics, proteomics & bioinformatics · 2016Article
- How computer simulations of the human heart can improve anti-arrhythmia therapy.The Journal of physiology · 2016Review
- Fast Simulation of Mechanical Heterogeneity in the Electrically Asynchronous Heart Using the MultiPatch Module.PLoS computational biology · 2015Article
- Article
- Patient-specific generation of the Purkinje network driven by clinical measurements of a normal propagation.Medical & biological engineering & computing · 2014Article
- Myocardial motion and deformation patterns in an experimental swine model of acute LBBB/CRT and chronic infarct.The international journal of cardiovascular imaging · 2014Article
- An automatic service for the personalization of ventricular cardiac meshes.Journal of the Royal Society, Interface · 2014Article
Corrections and comments
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Authors and funding
22 authors.
Funding
Abstract
This manuscript describes our recent developments towards better understanding of the mechanisms amenable to cardiac resynchronization therapy response. We report the results from a full multimodal dataset corresponding to eight patients from the euHeart project. The datasets include echocardiography, MRI and electrophysiological studies. We investigate two aspects. The first one focuses on pre-operative multimodal image data. From 2D echocardiography and 3D tagged MRI images, we compute atlas based dyssynchrony indices. We complement these indices with presence and extent of scar tissue and correlate them with CRT response. The second one focuses on computational models. We use pre-operative imaging to generate a patient-specific computational model. We show results of a fully automatic personalized electromechanical simulation. By case-per-case discussion of the results, we highlight the potential and key issues of this multimodal pipeline for the understanding of the mechanisms of CRT response and a better patient selection.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.