ReviewOral and maxillofacial surgery2014
Implants in bone: part II. Research on implant osseointegration: material testing, mechanical testing, imaging and histoanalytical methods.
Review in Oral and maxillofacial surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 58 citations in OpenAlex.
- Compressive Strength Optimization of 3D-Printed Voronoi Trabecular Bone Using the Taguchi Method.Biomimetics (Basel, Switzerland) · 2025Article
- Implant Surface Variability Between Progressive Knife-Edge Thread Design and International Organization for Standardization Thread with and Without Tapping Area: A Model Analysis.Materials (Basel, Switzerland) · 2025Article
- The Impact of Implant Surface Modifications on the Osseointegration Process: An Overview.Cureus · 2025Review
- Calibration of Aseptic Loosening Simulation for Coatings Osteoinductive Effect.Annals of biomedical engineering · 2025Article
- Histomorphometric Analysis of Osseointegrated Intraosseous Dental Implants Using Undecalcified Specimens: A Scoping Review.Biomimetics (Basel, Switzerland) · 2024Article
- Improved Biocompatibility and Osseointegration of Nanostructured Calcium-Incorporated Titanium Implant Surface Treatment (XPEEDMaterials (Basel, Switzerland) · 2024Article
- Titanium micro-nano textured surface with strontium incorporation improves osseointegration: an in vivo and in vitro study.Journal of applied oral science : revista FOB · 2024Article
- Antibiotic prophylaxis dysregulates dental implant placement surgery-induced osteoimmune wound healing and attenuates the alveolar bone-implant interface in mice.Journal of clinical periodontology · 2023Article
- Nanostructured Calcium-Incorporated Surface Compared to Machined and SLA Dental Implants-A Split-Mouth Randomized Case/Double-Control Histological Human Study.Nanomaterials (Basel, Switzerland) · 2023Article
- Silica coated high performance oxide ceramics promote greater ossification than titanium implants: an in vivo study.Journal of orthopaedic surgery and research · 2023Article
- Histomorphometrical and CBCT Evaluation of Tissue Loss Progression Induced by Consecutive, Alternate Ligatures in Experimental Peri-Implantitis in a Dog Model: A Pilot Study.Journal of clinical medicine · 2022Article
- Measures of Corticalization.Journal of clinical medicine · 2022Article
- Marginal bone loss around crestal or subcrestal dental implants: prospective clinical study.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2022Article
- Functionalised High-Performance Oxide Ceramics with Bone Morphogenic Protein 2 (BMP-2) Induced Ossification: An In Vivo Study.Life (Basel, Switzerland) · 2022Article
- Osseointegration of Zirconia Implants after UV-Light or Cold Atmospheric Plasma Surface Treatment In Vivo.Materials (Basel, Switzerland) · 2022Article
- A novel surgical model for the preclinical assessment of the osseointegration of dental implants: a surgical protocol and pilot study results.Journal of translational medicine · 2021Article
- [Research progress on the osseointegration of titanium implants promoted by cold atmospheric plasma].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2020Review
- Osseous ingrowth in allogeneic bone blocks applied for vertical bone augmentation: a preclinical randomised controlled study.Clinical oral investigations · 2020Article
- A new standardized critical size bone defect model in the pig forehead for comparative testing of bone regeneration materials.Clinical oral investigations · 2020Article
- Development of a quantitative preclinical screening model for implant osseointegration in rat tail vertebra.Clinical oral investigations · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn order to determine whether a newly developed implant material conforms to the requirements of biocompatibility, it must undergo rigorous testing. To correctly interpret the results of studies on implant material osseointegration, it is necessary to have a sound understanding of all the testing methods. The aim of this overview is to elucidate the methods that are used for the experimental evaluation of the osseointegration of implant materials. DISCUSSION: In recent decades, there has been a constant proliferation of new materials and surface modifications in the field of dental implants. This continuous development of innovative biomaterials requires a precise and detailed evaluation in terms of biocompatibility and implant healing before clinical use. The current gold standard is in vivo animal testing on well validated animal models. However, long-term outcome studies on patients have to follow to finally validate and show patient benefit.
conclusionNo experimental set-up can provide answers for all possible research questions. However, a certain transferability of the results to humans might be possible if the experimental set-up is carefully chosen for the aspects and questions being investigated. To enhance the implant survival rate in the rising number of patients with chronic diseases which compromise wound healing and osseointegration, dental implant research on compromised animal models will further gain importance in future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.