Evidence map›Paper›PMID 23429883›Full record

ReviewDer Urologe. Ausg. A2013

[Seminal cytokines: is quantification useful in urogenital disorders?].

A Pilatz, C Hudemann, F Wagenlehner, H-C Schuppe, T Diemer, W Weidner, H Renz, T Bschleipfer

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Urogenital Infection as a Risk Factor for Male Infertility.Deutsches Arzteblatt international · 2017
    Pooled it
  2. Age-Related COVID-19 Influence on Male Fertility.International journal of molecular sciences · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A PilatzKlinik für Urologie, Kinderurologie und Andrologie, Justus-Liebig-Universität Gießen, Universitätsklinikum Gießen und Marburg GmbH, Rudolf-Buchheim-Straße 7, 35392 Gießen, Deutschland. adrian.pilatz@chiru.med.uni-giessen.de
C Hudemann
F Wagenlehner
H-C Schuppe
T Diemer
W Weidner
H Renz
T Bschleipfer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytokines are cellular messengers which play a key role in many biological conditions such as immune defence and reproduction. During recent years analysis of seminal cytokines has become of increasing interest in various pathologies. To evaluate the current role of seminal cytokines we performed a systematic literature search within the framework of our focus group "Male Infertility during Infection and Inflammation - MIBIE". Out of 581 manuscripts we identified 124 original articles which investigated a total of 31 different cytokines. These studies can be categorized according to the following three topics: infertility, infections and chronic prostatitis. The current analysis demonstrates that seminal cytokine profiles are not associated with either semen quality or fertility; however, cytokines might be beneficial for diagnosis and monitoring therapy in patients with urogenital infections/inflammation. Further studies are needed to clarify if a single cytokine or a combination of different cytokines is necessary to evaluate different pathologies.

Indexed as

BiomarkersComorbidityCytokinesHumansInfertility, MaleMaleMale Urogenital DiseasesPrevalenceRisk AssessmentSeminal Plasma ProteinsBiomarkersCytokinesSeminal Plasma Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.