Evidence map›Paper›PMID 23426525›Full record

ArticleBiostatistics (Oxford, England)2013

Estimating incremental cost-effectiveness ratios and their confidence intervals with different terminating events for survival time and costs.

Shuai Chen, Hongwei Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biostatistics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shuai ChenDepartment of Statistics, Texas A&M University, College Station, TX 77843, USA. shuai@stat.tamu.edu
Hongwei Zhao

Funding

A Unified Approach of Cost-Effectiveness AnalysisR01HL096575 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI BANG, HEEJUNG · 2009 to 2011
$534k
NHLBI NIH HHS R01 HL096575
6 · The paper itself

Abstract

Cost-effectiveness analysis (CEA) is an important component of the economic evaluation of new treatment options. In many clinical and observational studies of costs, censored data pose challenges to the CEA. We consider a special situation where the terminating events for the survival time and costs are different. Traditional methods for statistical inference offer no means for dealing with censored data in these circumstances. To address this gap, we propose a new method for deriving the confidence interval for the incremental cost-effectiveness ratio. The simulation studies and real data example show that our method performs very well for some practical settings, revealing a great potential for application to actual settings in which terminating events for the survival time and costs differ.

Indexed as

BiostatisticsCardiac Resynchronization TherapyComputer SimulationConfidence IntervalsCost-Benefit AnalysisDefibrillators, ImplantableHealth Care CostsHeart DiseasesHeart FailureHumansRandomized Controlled Trials as TopicCensored dataCost-effectiveness analysisDifferent terminating eventsFieller methodSurvival analysis

Identifiers

PMID23426525
PMCPMC3732026

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.