Evidence map›Paper›PMID 23426328›Full record

ReviewCurrent opinion in infectious diseases2013

Long-term prognosis in community-acquired pneumonia.

Marcos I Restrepo, Paola Faverio, Antonio Anzueto

Registry-linked trialAbstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02141009 (Response to Pneumococcal Vaccination in Patients After Community Acquired Pneumonia With Streptococcus Pneumoniae Compared to Pneumonia Patients With Another Pathogen.), which is not on this map. Cited by 67 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02141009 phase4completednot on this mapstarted 2014, after this paper: background citation

Response to Pneumococcal Vaccination in Patients After Community Acquired Pneumonia With Streptococcus Pneumoniae Compared to Pneumonia Patients With Another Pathogen.

TypeinterventionalSponsorSt. Antonius HospitalRan2014 to 2014Enrolled60ConditionsPneumonia, Streptococcus Pneumoniae, Immune ResponseArmsPrevnar 13
3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Prolonged higher dose methylprednisoloneThe European respiratory journal · 2023
    Trial
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  7. Trial
  8. Trial
  9. Observational
  10. Impact of pneumococcal urinary antigen testing on clinical outcomes in patients hospitalized with community-acquired pneumonia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Observational
  15. Article
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  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcos I RestrepoUniversity of Texas Health Science Center at San Antonio, Texas, USA.
Paola Faverio
Antonio Anzueto

Funding

Effect of macrolides as immunomodulators in patients with sepsis and pneumoniaK23HL096054 · NHLBI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI RESTREPO, MARCOS I. · 2010 to 2014
$689k
NHLBI NIH HHS K23 HL096054NHLBI NIH HHS K23HL096054
6 · The paper itself

Abstract

purpose of reviewPneumonia is considered the leading infectious diseases cause of death and the seventh leading cause of death overall in the US. There is significant interest in understanding the relationship between community-acquired pneumonia (CAP) and mortality. RECENT

findingsMost clinical studies examining patients with CAP have used an arbitrary in-hospital or 30-day mortality as a short-term mortality clinical end point. However, long-term mortality (arbitrary >3 months) factors, incidence, prediction, and implications on patient care are important issues that require further evaluation in patients with CAP. This review focuses on the most recent literature assessing the importance and the frequency of long-term associated outcomes in patients with CAP, the risk factors, and possible implications for future strategies. Multiple risk factors that include age, sex, comorbid conditions, type of pneumonia, and severity of illness are associated with higher long-term mortality. In addition, several biomarkers were demonstrated to be independently associated with long-term mortality. SUMMARY: Despite advances in the understanding of long-term mortality among CAP patients, there is still a high unacceptable long-term mortality. Public health programs should address this important gap, considering the high level of complexity factors in patients with CAP.

Indexed as

BiomarkersCommunity-Acquired InfectionsHospital MortalityHumansOutcome Assessment, Health CarePneumoniaPrognosisRisk FactorsBiomarkers

Identifiers

PMID23426328
PMCPMC4066634

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.