ArticleFrontiers in immunology2013
The smallest unit: effector and memory CD8(+) T cell differentiation on the single cell level.
Article in Frontiers in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Survival and division fate programs are preserved but retuned during the naïve to memory CD8Immunology and cell biology · 2024Article
- Modes of Communication between T Cells and Relevance for Immune Responses.International journal of molecular sciences · 2020Review
- Lymphatic endothelial cells prime naïve CD8Nature communications · 2020Article
- Paracrine costimulation of IFN-γ signaling by integrins modulates CD8 T cell differentiation.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Protection by and maintenance of CD4 effector memory and effector T cell subsets in persistent malaria infection.PLoS pathogens · 2018Article
- Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation.Frontiers in immunology · 2018Review
- Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8Frontiers in immunology · 2018Review
- Self-renewal capacity of semi-differentiated CD8Annals of translational medicine · 2017Article
- Persistent infections, immune-senescence and Alzheimer's disease.Oncoscience · 2016Article
- CD8(+) T cell diversification by asymmetric cell division.Nature immunology · 2015Article
- Two distinct effector memory cell populations of WT1 (Wilms' tumor gene 1)-specific cytotoxic T lymphocytes in acute myeloid leukemia patients.Cancer immunology, immunotherapy : CII · 2015Article
- Engineering human peripheral blood stem cell grafts that are depleted of naïve T cells and retain functional pathogen-specific memory T cells.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014Article
- Polarized cells, polarized views: asymmetric cell division in hematopoietic cells.Frontiers in immunology · 2014Review
- Asymmetry of Cell Division in CFSE-Based Lymphocyte Proliferation Analysis.Frontiers in immunology · 2013Review
- Keeping memories alive.Frontiers in immunology · 2013Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CD8(+) T cell immune responses provide immediate protection against primary infection and durable memory capable of rapidly fighting off re-infection. Immediate protection and lasting memory are implemented by phenotypically and functionally distinct T cell subsets. While it is now widely accepted that these diverge from a common source of naïve T cells (T(n)), the developmental relation and succession of effector and memory T cell subsets is still under intense debate. Recently, a distinct memory T cell subset has been suggested to possess stem cell-like features, sparking the hope to harness its capacity for self-renewal and diversification for successful therapy of chronic infections or malignant diseases. In this review we highlight current developmental models of memory generation, T cell subset diversification and T cell stemness. We discuss the importance of single cell monitoring techniques for adequately mapping these developmental processes and take a brief look at signaling components active in the putative stem cell-like memory T cell compartment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.