ArticleDepression and anxiety2013
Attention-deficit/hyperactivity disorder in adolescence predicts onset of major depressive disorder through early adulthood.
Article in Depression and anxiety, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 113 citations in OpenAlex.
- The effect of the physical exercise intervention on negative emotions in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Loneliness in Young People with ADHD: A Systematic Review and Meta-Analysis.Journal of attention disorders · 2024Pooled it
- Psychological and contextual risk factors for first-onset depression among adolescents and young people around the globe: A systematic review and meta-analysis.Early intervention in psychiatry · 2023Pooled it
- Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals: A Meta-analysis.JAMA psychiatry · 2020Pooled it
- Bright light therapy versus physical exercise to prevent co-occurring depression in adolescents and young adults with attention-deficit/hyperactivity disorder: a multicentre, three-arm, randomised controlled, pilot phase-IIa trial.European archives of psychiatry and clinical neuroscience · 2025Trial
- Do ADHD symptoms in adolescence predict psychiatric disorders later in life? A longitudinal study of the Northern Finland birth cohort 1986.Social psychiatry and psychiatric epidemiology · 2026Article
- Identifying Candidate Mediators Linking ADHD Symptoms and Internalising Problems in Adolescence: An Exploratory Longitudinal Mediation Analysis.Journal of attention disorders · 2026Article
- Linking ADHD to Depression in Adolescents: the Mediating Role of Social Skills.Research on child and adolescent psychopathology · 2026Article
- Transgender and gender-diverse autistic adolescents are at elevated risk of depression.Autism : the international journal of research and practice · 2026Article
- Adult-diagnosed and childhood-diagnosed attention deficit/hyperactivity disorder: cognitive and environmental contributions to symptom severity across different age of diagnosis.Frontiers in psychiatry · 2026Article
- Attention-Deficit/Hyperactivity Disorder, Self-Reported Mental Health, and Weight Loss 10 Years after Metabolic-Bariatric Surgery during Adolescence.Obesity facts · 2025Article
- Emotion regulation as a transdiagnostic link between ADHD and depression symptoms: evidence from a network analysis of youth in the ABCD study.Child and adolescent psychiatry and mental health · 2025Article
- Comparing DSM-5 Pathological Personality Traits in Youths With ADHD, Subthreshold ADHD, and Healthy Controls Using the Personality Inventory for DSM-5 (PID-5): A Network Analysis Study.Journal of autism and developmental disorders · 2025Article
- Comorbidity and temporal associations between mental disorders among college students in the world mental health international college student initiative.Psychiatry research · 2025Article
- Attention-Deficit/Hyperactivity Disorder Symptoms Are Common and Associated with Worse Glycemic Control in Adults with Type 1 Diabetes.Journal of clinical medicine · 2025Article
- Networks of Neurodevelopmental Traits, Socioenvironmental Factors, Emotional Dysregulation in Childhood, and Depressive Symptoms Across Development in Two U.K. Cohorts.The American journal of psychiatry · 2023Article
- Associations Between Adult Attention-Deficit/Hyperactivity Disorder (ADHD) Traits and Sociodemographic Characteristics in Japanese Workers.Neuropsychiatric disease and treatment · 2023Article
- Practitioner Review: Attention-deficit hyperactivity disorder and autism spectrum disorder - the importance of depression.Journal of child psychology and psychiatry, and allied disciplines · 2023Review
- ADHD in adults with major depressive or bipolar disorder: does it affect clinical features, comorbidity, quality of life, and global functioning?BMC psychiatry · 2022Article
- Depressive symptoms in youth with ADHD: the role of impairments in cognitive emotion regulation.European archives of psychiatry and clinical neuroscience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThe aim of this study was to examine the prospective relationship between a history of attention-deficit/hyperactivity disorder (ADHD) assessed in mid-adolescence and the onset of major depressive disorder (MDD) through early adulthood in a large school-based sample. A secondary aim was to examine whether this relationship was robust after accounting for comorbid psychopathology and psychosocial impairment.
methodOne thousand five hundred seven participants from the Oregon Adolescent Depression Project completed rating scales in adolescence and structured diagnostic interviews up to four times from adolescence to age 30.
resultsAdolescents with a lifetime history of ADHD were at significantly higher risk of MDD through early adulthood relative to those with no history of ADHD. ADHD remained a significant predictor of MDD after controlling for gender, lifetime history of other psychiatric disorders in adolescence, social and academic impairment in adolescence, stress and coping in adolescence, and new onset of other psychiatric disorders through early adulthood (hazard ratio, 1.81; 95% confidence interval, 1.04, 3.06). Additional significant, robust predictors of MDD included female gender, a lifetime history of an anxiety disorder, and poor coping skills in mid-adolescence, as well as the onset of anxiety, oppositional defiant disorder, and substance-use disorder after mid-adolescence.
conclusionsA history of ADHD in adolescence was associated with elevated risk of MDD through early adulthood and this relationship remained significant after controlling for psychosocial impairment in adolescence and co-occurring psychiatric disorders. Additional work is needed to identify the mechanisms of risk and to inform depression prevention programs for adolescents with ADHD.
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