ArticleJournal of materials science. Materials in medicine2013
Corrosion and in vitro biocompatibility properties of cryomilled-spark plasma sintered commercially pure titanium.
Article in Journal of materials science. Materials in medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Modulating the crystallinity of biphasic calcium phosphate composites balances surface and ionic cues to enhance osteogenesis via integrin-mediated cytoskeletal signaling.Materials today. Bio · 2025Article
- The preparation and characterization of graphene oxide-multiwalled minocycline coatings on ultrafine-grained titanium implants for enhanced performance studies.Frontiers in oral health · 2025Article
- Microleakage at the Different Implant Abutment Interface: A Systematic Review.Journal of clinical and diagnostic research : JCDR · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ti alloys, such as Ti6Al4V, are currently used in biomedical and dental implant applications. Ti alloys are used because they are stronger than commercially pure (CP) Ti due to the presence of alloying elements. However, toxicity of alloying elements during long-term use of implants is of concern. Another means of increasing the strength of materials is grain size refinement. In this study, ultrafine-grained (UFG, ~250 nm to 1 μm) CP Ti was produced by cryomilling followed by spark plasma sintering (SPS). Electrochemical impedance spectroscopy (EIS) and cell culture experiments were performed to compare the corrosion and biocompatibility properties of coarse grained (CG) Ti and UFG Ti. It was found that UFG Ti exhibited corrosion resistance comparable to CG Ti in Ringers solution. In addition, UFG Ti exhibited a reduced inflammatory response and enhanced cell adhesion compared to CG Ti. Investigation of surface roughness provided an explanation for enhanced cell adhesion.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.