Evidence map›Paper›PMID 23423472›Full record

ArticleScandinavian journal of work, environment & health2013

Prevalence and incidence of carpal tunnel syndrome in US working populations: pooled analysis of six prospective studies.

Ann Marie Dale, Carisa Harris-Adamson, David Rempel, Fred Gerr, Kurt Hegmann, Barbara Silverstein, Susan Burt, Arun Garg, Jay Kapellusch, Linda Merlino and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scandinavian journal of work, environment & health, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 11 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 11 syntheses or guidelines pooled it, 324 citations in OpenAlex.

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  3. Hormone replacement therapy in women and risk of carpal tunnel syndrome: a systematic review and metaanalysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2023
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76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 1 country.

Ann Marie DaleDivision of General Medical Science, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8005, St Louis, MO 63110, USA. adale@dom.wustl.edu
Carisa Harris-Adamson
David Rempel
Fred Gerr
Kurt Hegmann
Barbara Silverstein
Susan Burt
Arun Garg
Jay Kapellusch
Linda Merlino
Matthew S Thiese
Ellen A Eisen
Bradley Evanoff
United States Department of State · USUniversity of California, Berkeley · USWashington University in St. Louis · USNational Institute for Occupational Safety and Health · USRocky Mountain University of Health Professions · USSamuel Merritt University · USUniversity of California, San Francisco · USUniversity of Iowa · USUniversity of Wisconsin–Milwaukee · US

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
A Pooled Longitudinal Analysis of Workplace Carpal Tunnel SyndromeR01OH009712 · OH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI REMPEL, DAVID M · 2010 to 2012
$1.5M
NCATS NIH HHS UL1 TR000448NCRR NIH HHS UL1 RR024992NIOSH CDC HHS 5R01OH009712NIOSH CDC HHS R01 OH009712
6 · The paper itself

Abstract

objectivesMost studies of carpal tunnel syndrome (CTS) incidence and prevalence among workers have been limited by small sample sizes or restricted to a small subset of jobs. We established a common CTS case definition and then pooled CTS prevalence and incidence data across six prospective studies of musculoskeletal outcomes to measure CTS frequency and allow better studies of etiology.

methodsSix research groups collected prospective data at > 50 workplaces including symptoms characteristic of CTS and electrodiagnostic studies (EDS) of the median and ulnar nerves across the dominant wrist. While study designs and the timing of data collection varied across groups, we were able to create a common CTS case definition incorporating both symptoms and EDS results from data that were collected in all studies.

resultsAt the time of enrollment, 7.8% of 4321 subjects met our case definition and were considered prevalent cases of CTS. During 8833 person-years of follow-up, an additional 204 subjects met the CTS case definition for an overall incidence rate of 2.3 CTS cases per 100 person-years.

conclusionsBoth prevalent and incident CTS were common in data pooled across multiple studies and sites. The large number of incident cases in this prospective study provides adequate power for future exposure-response analyses to identify work- and non-work-related risk factors for CTS. The prospective nature allows determination of the temporal relations necessary for causal inference.

Indexed as

Carpal Tunnel SyndromeFemaleHumansIncidenceMalePrevalenceUnited States

Identifiers

PMID23423472
PMCPMC4042862
OpenAlexW2107605951

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.