ArticleThe Journal of biological chemistry2013
Sequence analysis and domain motifs in the porcine skin decorin glycosaminoglycan chain.
Article in The Journal of biological chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Comparative Study on the Characterization of Myofibrillar Proteins from Tilapia, Golden Pompano and Skipjack Tuna.Foods (Basel, Switzerland) · 2022Article
- Analysis of the Glycosaminoglycan Chains of Proteoglycans.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021Review
- Glycosaminoglycan Domain Mapping of Cellular Chondroitin/Dermatan Sulfates.Scientific reports · 2020Article
- The dual role of the glycosaminoglycan chondroitin-6-sulfate in the development, progression and metastasis of cancer.The FEBS journal · 2019Review
- LC-MS/MS characterization of xyloside-primed glycosaminoglycans with cytotoxic properties reveals structural diversity and novel glycan modifications.The Journal of biological chemistry · 2018Article
- Sequencing the Dermatan Sulfate Chain of Decorin.Journal of the American Chemical Society · 2017Article
- Purification and sequence characterization of chondroitin sulfate and dermatan sulfate from fishes.Glycoconjugate journal · 2017Article
- Identification of keratan sulfate disaccharide at C-3 position of glucuronate of chondroitin sulfate from Mactra chinensis.The Biochemical journal · 2016Article
- Proteoglycans and their heterogeneous glycosaminoglycans at the atomic scale.Biomacromolecules · 2015Article
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- A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra.Molecular & cellular proteomics : MCP · 2014Article
- A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function.Matrix biology : journal of the International Society for Matrix Biology · 2014Article
- Carbohydrate-containing molecules as potential biomarkers in colon cancer.Omics : a journal of integrative biology · 2014Article
- Analysis of glycosaminoglycan-derived, precolumn, 2-aminoacridone-labeled disaccharides with LC-fluorescence and LC-MS detection.Nature protocols · 2014Article
- Expression of heparanase in basal cell carcinoma and squamous cell carcinoma.Anais brasileiros de dermatologiaArticle
Corrections and comments
- Erratum issuedSolakylidirim, Kemal [corrected to Solakyildirim, Kemal]
Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
Abstract
Decorin proteoglycan is comprised of a core protein containing a single O-linked dermatan sulfate/chondroitin sulfate glycosaminoglycan (GAG) chain. Although the sequence of the decorin core protein is determined by the gene encoding its structure, the structure of its GAG chain is determined in the Golgi. The recent application of modern MS to bikunin, a far simpler chondroitin sulfate proteoglycans, suggests that it has a single or small number of defined sequences. On this basis, a similar approach to sequence the decorin of porcine skin much larger and more structurally complex dermatan sulfate/chondroitin sulfate GAG chain was undertaken. This approach resulted in information on the consistency/variability of its linkage region at the reducing end of the GAG chain, its iduronic acid-rich domain, glucuronic acid-rich domain, and non-reducing end. A general motif for the porcine skin decorin GAG chain was established. A single small decorin GAG chain was sequenced using MS/MS analysis. The data obtained in the study suggest that the decorin GAG chain has a small or a limited number of sequences.
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Registered trials
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