ArticleAnalytical chemistry2013
Scanning ion conductance microscopy measurement of paracellular channel conductance in tight junctions.
Article in Analytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 65 citations in OpenAlex.
- Live-Cell SICM Imaging: An Introductory Guide for New Users.Analytical chemistry · 2026Article
- Single-Cell Analysis with Spatiotemporal Control of Local pH.ACS measurement science au · 2025Article
- Operando Scanning Electrochemical Probe Microscopy during Electrocatalysis.Chemical reviews · 2023Review
- The New Era of High-Throughput Nanoelectrochemistry.Analytical chemistry · 2023Review
- Scanning Ion Conductance Microscopy.Chemical reviews · 2021Review
- A Hybrid Nanofiber/Paper Cell Culture Platform for Building a 3D Blood-brain Barrier Model.Small methods · 2021Article
- Scanning ion conductance microscopy of isolated metaphase chromosomes in a liquid environment.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- Scanning Ion Conductance Microscopy Study Reveals the Disruption of the Integrity of the Human Cell Membrane Structure by Oxidative DNA Damage.ACS applied bio materials · 2021Article
- Quantifying single-platelet biomechanics: An outsider's guide to biophysical methods and recent advances.Research and practice in thrombosis and haemostasis · 2020Review
- Imaging effects of hyperosmolality on individual tricellular junctions.Chemical science · 2020Article
- Measuring the Permeability of Endothelial Cell Monolayers: Teaching New Tricks to an Old Dog.Biophysical journal · 2019Article
- Review
- Multifunctional scanning ion conductance microscopy.Proceedings. Mathematical, physical, and engineering sciences · 2017Review
- Nanopore Sensing.Analytical chemistry · 2017Review
- Claudins and mineral metabolism.Current opinion in nephrology and hypertension · 2016Review
- Biochemical and biophysical analyses of tight junction permeability made of claudin-16 and claudin-19 dimerization.Molecular biology of the cell · 2015Article
- Article
- Ion channel probes for scanning ion conductance microscopy.Langmuir : the ACS journal of surfaces and colloids · 2014Article
- The kidney tight junction (Review).International journal of molecular medicine · 2014Review
- Potentiometric-scanning ion conductance microscopy for measurement at tight junctions.Tissue barriers · 2013Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Elucidation of epithelial transport across transcellular or paracellular pathways promises to advance the present understanding of ion transport and enables regulation of cell junctions critical to the cell and molecular biology of the epithelium. Here, we demonstrate a new instrumental technique, potentiometric scanning ion conductance microscopy (P-SICM), that utilizes a nanoscale pipet to differentiate paracellular and transcellular transport processes at high spatial resolution. The technique is validated for well-defined polymer membranes and then employed to study wild type and claudin-deficient mutants of Madin-Darby Canine Kidney strain II (MDCKII) cells. Paracellular permeabilities conferred by claudin-2 are captured by P-SICM which demonstrates the utility to monitor apparent conductance at subcellular levels.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.