Evidence map›Paper›PMID 23420858›Full record

ArticleDento maxillo facial radiology2013

Role of diffusion-weighted MRI in differentiation of masticator space malignancy from infection.

A A K Abdel Razek, N Nada

Open access · greenAbstract read
In one paragraph

Article in Dento maxillo facial radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 36 citations in OpenAlex.

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  12. Use of diffusion-weighted imaging (DWI) in PET/MRI for head and neck cancer evaluation.European journal of nuclear medicine and molecular imaging · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A A K Abdel RazekDepartment of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, Egypt. arazek@mans.edu.eg
N Nada
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to assess the role of the apparent diffusion coefficient (ADC) value in differentiation of masticator space malignancy from infection.

methodsA retrospective study of 49 patients (31 male and 18 female; age range 5-66 years) with masticator space lesion was conducted. They underwent spin-echo-type echo planar diffusion-weighted MRI of the head and neck with b-values of 0 mm(2) s(-1), 500 mm(2) s(-1) and 1000 mm(2) s(-1). The ADC maps were reconstructed and the ADC value of the masticator space lesion was calculated.

resultsThe mean (± standard deviation) ADC value of masticator space malignancy (0.91 ± 0.21 × 10(-3) mm(2) s(-1)) was significantly lower (p = 0.001) than that of masticator space infection (1.59 ± 0.32 × 10(-3) mm(2) s(-1)). When an ADC value of 1.20 × 10(-3) mm(2) s(-1) was used as a threshold value for differentiating masticator space malignancy from infection, the best result was obtained with an accuracy of 88%, sensitivity of 88%, specificity of 87%, negative predictive value of 94%, positive predictive value of 86% and area under the curve of 0.92. There was a significant difference in the ADC value between squamous cell carcinoma and soft tissue sarcoma (p = 0.001), as well as between bacterial and fungal infection of the masticator space (p = 0.001).

conclusionWe concluded that ADC value is a non-invasive promising imaging parameter that can be used for differentiation of masticator space malignancy from infection.

Indexed as

AdolescentAdultAgedBacterial InfectionsCarcinoma, Squamous CellChildChild, PreschoolDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingEcho-Planar ImagingEdemaFacial PainFemaleFollow-Up StudiesHead and Neck NeoplasmsHumans

Identifiers

PMID23420858
PMCPMC3667512
OpenAlexW2137933494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.