Evidence map›Paper›PMID 23420476›Full record

ArticlePrevention science : the official journal of the Society for Prevention Research2013

Early adverse care, stress neurobiology, and prevention science: lessons learned.

Jacqueline Bruce, Megan R Gunnar, Katherine C Pears, Philip A Fisher

Abstract read
In one paragraph

Article in Prevention science : the official journal of the Society for Prevention Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. The Neurobiology of Social Distance.Trends in cognitive sciences · 2020
    Review
  13. Early adversity, child neglect, and stress neurobiology: From observations of impact to empirical evaluations of mechanisms.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2019
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacqueline BruceOregon Social Learning Center, 10 Shelton McMurphey Boulevard, Eugene, OR 97401-2426, USA. jackieb@oslc.org
Megan R Gunnar
Katherine C Pears
Philip A Fisher

Funding

Project 3: The neurobiology of adverse early care in rhesus infants....P50MH078105 · NIMH · UNIVERSITY OF MINNESOTA · PI GUNNAR, MEGAN R · 2009 to 2013
$9.9M
NIMH NIH HHS P50 MH078105
6 · The paper itself

Abstract

There is growing evidence that some of the difficulties observed among children who have experienced early adverse care (e.g., children internationally adopted from institutional care and maltreated children in foster care) involve experience-induced alterations in stress-responsive neurobiological systems, including the hypothalamic-pituitary-adrenocortical (HPA) system. Thus, incorporating stress neurobiology into prevention research could aid in identifying the children most in need of preventive intervention services, elucidating the mechanisms of change in effective interventions, and providing insight into the differential responses of children to effective interventions. However, integrating stress neurobiology and prevention research is challenging. In this paper, the results of studies examining HPA system activity in children who have experienced early adverse care are reviewed, the implications of these results for prevention research are discussed, and critical steps for successfully incorporating stress neurobiology into prevention research are identified.

Indexed as

HumansHypothalamo-Hypophyseal SystemPituitary-Adrenal SystemStress, Psychological

Identifiers

PMID23420476
PMCPMC3633628

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.