ArticleCancer causes & control : CCC2013
Dietary intake of vegetables, folate, and antioxidants and the risk of Barrett's esophagus.
Article in Cancer causes & control : CCC, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 5 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 5 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Risk Factors for the Development of Barrett's Esophagus and Esophageal Adenocarcinoma: A Systematic Review and Meta-Analysis.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- Lifestyle interventions can reduce the risk of Barrett's esophagus: a systematic review and meta-analysis of 62 studies involving 250,157 participants.Cancer medicine · 2021Pooled it
- Flavonoids, Flavonoid Subclasses, and Esophageal Cancer Risk: A Meta-Analysis of Epidemiologic Studies.Nutrients · 2016Pooled it
- Dietary fruit, vegetable, fat, and red and processed meat intakes and Barrett's esophagus risk: a systematic review and meta-analysis.Scientific reports · 2016Pooled it
- Citrus Fruit Intake Substantially Reduces the Risk of Esophageal Cancer: A Meta-Analysis of Epidemiologic Studies.Medicine · 2015Pooled it
- The Role of a Plant-Only (Vegan) Diet in Gastroesophageal Reflux Disease: Online Survey of the Italian General Population.Nutrients · 2023Article
- Role of Obesity, Physical Exercise, Adipose Tissue-Skeletal Muscle Crosstalk and Molecular Advances in Barrett's Esophagus and Esophageal Adenocarcinoma.International journal of molecular sciences · 2022Review
- Dietary Habits and Risk of Esophagitis and Barrett's Esophagus: A Multicenter Italian Case-Control Study.Digestive diseases and sciences · 2021Article
- Dietary and Lifestyle Factors Related to Gastroesophageal Reflux Disease: A Systematic Review.Therapeutics and clinical risk management · 2021Review
- Dietary antioxidant intake and the risk of developing Barrett's oesophagus and oesophageal adenocarcinoma.British journal of cancer · 2018Article
- Increased detection of Barrett's esophagus and esophageal dysplasia with adjunctive use of wide-area transepithelial sample with three-dimensional computer-assisted analysis (WATS).United European gastroenterology journal · 2018Article
- Association of sporadic and familial Barrett's esophagus with breast cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2018Article
- Can We Use Diet to Effectively Treat Esophageal Disease? A Review of the Current Literature.Current gastroenterology reports · 2017Review
- Dietary flavonoid intake and Barrett's esophagus in western Washington State.Annals of epidemiology · 2015Article
- Diet and upper gastrointestinal malignancies.Gastroenterology · 2015Review
- Dietary Risk Reduction Factors for the Barrett's Esophagus-Esophageal Adenocarcinoma Continuum: A Review of the Recent Literature.Current nutrition reports · 2015Article
- Dietary consumption of meat, fat, animal products and advanced glycation end-products and the risk of Barrett's oesophagus.Alimentary pharmacology & therapeutics · 2013Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeDiet is a potentially modifiable risk factor for Barrett's esophagus (BE). We investigated the associations between intakes of fruits and vegetables and risk of BE.
methodsWe identified study subjects from 1,859 participants who underwent the endoscopy in a single VA Medical Center in the US between 2008 and 2011. Dietary intake in the previous year was elicited using a self-administered Block food frequency questionnaire (FFQ). Logistic regression model was used to estimate odds ratio (OR) and its 95 % confidence interval (CI) for BE.
resultsA total of 151 cases with definite BE and 777 controls completed the FFQ. When highest tertile of intake was compared with the lowest, the OR (95 % CI) was 0.46 (0.26-0.81) for dark green vegetables, 0.52 (0.30-0.90) for legumes, 0.50 (0.28-0.90) for total fiber, 0.45 (0.25-0.81) for isoflavones, 0.52 (0.30-0.67) for total folate, and 0.45 (0.26-0.79) for lutein, adjusting for multiple confounding factors including use of aspirin or proton pump inhibitor, gastro-esophageal reflux symptoms, and physical activity. The association for dark green vegetables was attenuated after adjustment for lutein, total fiber, and total folate (OR = 0.82; 95 % CI 0.30-2.22).
conclusionHigher intake of dark green vegetables was associated with a decreased risk of BE in a veteran population. Such an inverse association may be partially mediated by lutein, fiber, and folate. The novel findings on the association between intake of lutein, total folate, or isoflavones and risk of BE need further confirmation.
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