ArticleJournal of assisted reproduction and genetics2013
Expression of G protein estrogen receptor (GPER) on membrane of mouse oocytes during maturation.
Article in Journal of assisted reproduction and genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 28 citations in OpenAlex.
- Interaction of GPER-1 with the endocrine signaling axis in breast cancer.Frontiers in endocrinology · 2025Review
- Estrogen Regulates CaBiomolecules · 2024Article
- Roles of estrogen and its receptors in polycystic ovary syndrome.Frontiers in cell and developmental biology · 2024Review
- Estradiol and Estrogen-like Alternative Therapies in Use: The Importance of the Selective and Non-Classical Actions.Biomedicines · 2022Review
- Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish.Frontiers in endocrinology · 2021Article
- Putative adverse outcome pathways for female reproductive disorders to improve testing and regulation of chemicals.Archives of toxicology · 2020Review
- GPER agonist G1 suppresses neuronal apoptosis mediated by endoplasmic reticulum stress after cerebral ischemia/reperfusion injury.Neural regeneration research · 2019Article
- Reconsidering the roles of endogenous estrogens and xenoestrogens: the membrane estradiol receptor G protein-coupled receptor 30 (GPR30) mediates the effects of various estrogens.The Journal of reproduction and development · 2018Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine expression of G-protein estrogen receptor (GPER) in mouse oocyte membrane during maturation.
methodsThe expression of GPER from different maturation stages of oocytes, in vivo and in vitro matured oocytes as well as aging oocytes was examined by immune-fluorescence GPR30 antibody and the images were analyzed by laser scanning confocal microscope. Further confirmation was performed by Western blots for cell fractionation.
resultsSignificant fluorescent signal was observed on the surface of mouse oocytes. The image expression was lower in germinal vesicle (GV) stage than mature metaphase-II (M-II) stage oocytes. There was high expression in in-vivo matured oocytes compared to in vitro matured oocytes. The highest expression was observed in aging oocytes compared with other oocytes.
conclusionsThe changes of expression of GPER on mouse oocytes plasma membrane confirm oocyte membrane maturation, suggesting that those changes of GPER may be related to the functional role of oocyte maturation.
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Registered trials
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