Evidence map›Paper›PMID 23419871›Full record

ArticleEpilepsy & behavior : E&B2013

Transcranial focal electrical stimulation via tripolar concentric ring electrodes does not modify the short- and long-term memory formation in rats evaluated in the novel object recognition test.

G Rogel-Salazar, H Luna-Munguía, K E Stevens, W G Besio

Open access · greenAbstract read
In one paragraph

Article in Epilepsy & behavior : E&B, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

G Rogel-SalazarDept of Electrical, Computer, and Biomedical Engineering, University of Rhode Island, 4 East Alumni Ave, Kingston, RI 02881, USA.
H Luna-Munguía
K E Stevens
W G Besio
University of Rhode Island · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Anticonvulsant effects of novel concentric ring electrode electrical stimulationR21NS061335 · NINDS · UNIVERSITY OF RHODE ISLAND · PI BESIO, WALTER GRANT · 2009 to 2010
$397k
A US-Mexico Collaborative Effort to Improve Epilepsy Control and DiagnosisR21TW009384 · FIC · UNIVERSITY OF RHODE ISLAND · PI BESIO, WALTER GRANT · 2012 to 2013
$200k
FIC NIH HHS R21 TW009384FIC NIH HHS R21TW009384NINDS NIH HHS R21 NS061335NINDS NIH HHS R21NS061335
6 · The paper itself

Abstract

Noninvasive transcranial focal electrical stimulation (TFS) via tripolar concentric ring electrodes (TCREs) has been under development as an alternative/complementary therapy for seizure control. Transcranial focal electrical stimulation has shown efficacy in attenuating penicillin-, pilocarpine-, and pentylenetetrazole-induced acute seizures in rat models. This study evaluated the effects of TFS via TCREs on the memory formation of healthy rats as a safety test of TFS. Short- and long-term memory formation was tested after the application of TFS using the novel object recognition (NOR) test. The following independent groups were used: naïve, control (without TFS), and TFS (treated). The naïve, control, and stimulated groups spent more time investigating the new object than the familiar one during the test phase. Transcranial focal electrical stimulation via TCREs given once does not modify the short- and long-term memory formation in rats in the NOR test. Results provide an important step towards a better understanding for the safe usage of TFS via TCREs.

Indexed as

ElectrodesAnalysis of VarianceAnimalsElectric StimulationExploratory BehaviorMaleMemoryMotor ActivityRatsRats, Sprague-DawleyRecognition, PsychologyTime Factors

Identifiers

PMID23419871
PMCPMC3606894
OpenAlexW2096853168

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.