ArticleJournal of clinical research in pediatric endocrinology2013
Diabetes care, glycemic control, complications, and concomitant autoimmune diseases in children with type 1 diabetes in Turkey: a multicenter study.
Article in Journal of clinical research in pediatric endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 48 citations in OpenAlex.
- Improving Diabetes Care Through Teamwork, Comprehensive Education, Tighter Goals, and Technology: Single-Center Data from TürkiyeJournal of clinical research in pediatric endocrinology · 2026Article
- Models of care for children and adolescents with type 1 diabetes in low- and middle-income countries: a scoping review.The Cochrane database of systematic reviews · 2025Article
- Current Management of Type 1 Diabetes in Children: Guideline-based Expert Opinions and RecommendationsJournal of clinical research in pediatric endocrinology · 2024Review
- Chronic Microvascular Complication of Type 1 Diabetes Mellitus and Its Predictors Among Children with Type 1 Diabetes Mellitus in Ethiopia; A Single Center Experience: Ambi Directional Cohort Study.Pediatric health, medicine and therapeutics · 2024Article
- Atypical comorbidities in a child considered to have type 1 diabetes led to the diagnosis of SLC29A3 spectrum disorder.Hormones (Athens, Greece) · 2022Review
- Effect of the COVID-19 quarantine on metabolic control in children and adolescents with type 1 diabetes.Endocrinologia, diabetes y nutricion · 2022Article
- Effect of the COVID-19 quarantine on metabolic control in children and adolescents with type 1 diabetes.Endocrinologia, diabetes y nutricion · 2021Article
- Frequency of Celiac Disease and Spontaneous Normalization Rate of Celiac Serology in Children and Adolescent Patients with Type 1 DiabetesJournal of clinical research in pediatric endocrinology · 2021Article
- Personal and Clinical Predictors of Poor Metabolic Control in Children with Type 1 Diabetes in Jordan.Journal of diabetes research · 2019Article
- The lung endothelin system: a potent therapeutic target with bosentan for the amelioration of lung alterations in a rat model of diabetes mellitus.Journal of endocrinological investigation · 2015Article
- National childhood diabetes program activities in Turkey.Journal of clinical research in pediatric endocrinology · 2015Article
- Glycemic control, complications, and associated autoimmune diseases in children and adolescents with type 1 diabetes in Jeddah, Saudi Arabia.Saudi medical journal · 2015Article
- Current trends in the monitoring and treatment of diabetic retinopathy in young adults.Mediators of inflammation · 2014Review
- Generating double knockout mice to model genetic intervention for diabetic cardiomyopathy in humans.Methods in molecular biology (Clifton, N.J.) · 2014Article
- Evaluation of ceftiofur-PHBV microparticles in rats.Drug design, development and therapy · 2014Article
- Celiac disease and autoimmune-associated conditions.BioMed research international · 2013Review
- Influence of puberty on retinal microcirculation in children with type 1 diabetes without retinopathy using optical coherence tomography angiography.Diabetes & vascular disease researchObservational
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Authors and funding
25 authors at 13 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveEpidemiologic and clinical features of type 1 diabetes mellitus (T1DM) may show substantial differences among countries. The primary goal in the management of T1DM is to prevent micro- and macrovascular complications by achieving good glycemic control. The present study aimed to assess metabolic control, presence of concomitant autoimmune diseases, and of acute and long-term complications in patients diagnosed with T1DM during childhood and adolescence. The study also aimed to be a first step in the development of a national registry system for T1DM, in Turkey.
methodsBased on hospital records, this cross-sectional, multicenter study included 1 032 patients with T1DM from 12 different centers in Turkey, in whom the diagnosis was established during childhood. Epidemiological and clinical characteristics of the patients were recorded. Metabolic control, diabetes care, complications, and concomitant autoimmune diseases were evaluated.
resultsMean age, diabetes duration, and hemoglobin A1c level were 12.5 ± 4.1 years, 4.7 ± 3.2 years, and 8.5 ± 1.6%, respectively. Acute complications noted in the past year included ketoacidosis in 5.2% of the patients and severe hypoglycemia in 4.9%. Chronic lymphocytic thyroiditis was noted in 12%, Graves' disease in 0.1%, and celiac disease in 4.3% of the patients. Chronic complications including neuropathy, retinopathy, and persistent microalbuminuria were present in 2.6%, 1.4%, and 5.4% of the patients, respectively. Diabetic nephropathy was not present in any of the patients. Mean diabetes duration and age of patients with neuropathy, retinopathy and microalbuminuria were significantly different from the patients without these long-term complications (p<0.01). A significant difference was found between pubertal and prepubertal children in terms of persistent microalbuminuria and neuropathy (p=0.02 and p<0.001, respectively). Of the patients, 4.4% (n:38) were obese and 5% had short stature; 17.4% of the patients had dyslipidemia, and 14% of the dyslipidemic patients were obese.
conclusionsAlthough the majority of the patients in the present study were using insulin analogues, poor glycemic control was common, and chronic complications were encountered.
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