ReviewNature reviews. Neurology2013
Controversies in defining and determining death in critical care.
Review in Nature reviews. Neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 92 citations in OpenAlex.
- Guideline
- A structured analysis of the concept of brain death.Theoretical medicine and bioethics · 2026Article
- The History of Donation after Circulatory Death (DCD): Backlash and Boomerang.Neurocritical care · 2024Article
- Rationale for revisions to the definition of death and criteria for its determination in Canada.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023Article
- Organ donation in the surgical ICU: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document.Trauma surgery & acute care open · 2023Article
- The neuroethics of disorders of consciousness: a brief history of evolving ideas.Brain : a journal of neurology · 2021Article
- Evaluating the translational value of postmortem brain reperfusion technology.Translational neuroscience · 2021Article
- The ethical obligation of the dead donor rule.Medicine, health care, and philosophy · 2020Article
- Death determined by neurological criteria: the next steps.Intensive care medicine · 2017Article
- Current controversies in brain death determination.Nature reviews. Neurology · 2017Review
- Physician Power to Declare Death by Neurologic Criteria Threatened.Neurocritical care · 2017Article
- Donation after brain circulation determination of death.BMC medical ethics · 2017Article
- Revisiting the Persisting Tension Between Expert and Lay Views About Brain Death and Death Determination: A Proposal Inspired by Pragmatism.Journal of bioethical inquiry · 2015Article
- Article
- Transplantation: pulsatile perfusion-time for a prospective trial.Nature reviews. Nephrology · 2014Article
- Ethical and legal implications of elective ventilation and organ transplantation: "medicalization" of dying versus medical mission.BioMed research international · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circulatory-respiratory or brain tests are widely accepted for definition and determination of death, but have several controversial issues. Both determinations have been stimulated by organ donation, but must be valid independently of this process. Current controversies in brain death include whether the definition is conceptually coherent, whether the whole-brain or brainstem criterion is correct, whether one neurological examination or two should be required, and when to conduct the examination following therapeutic hypothermia. Controversies about the circulatory determination of death include the minimum duration of asystole that is sufficient for death to be declared, and whether the distinction between permanent and irreversible cessation of circulatory functioning is important. In addition, the goal of organ donation raises issues such as the optimal way to time and conduct the request conversation with family members of the patient, and whether the Dead Donor Rule should be abandoned.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.