ArticlePloS one2013
Measurement of pancreatic volume by abdominal MRI: a validation study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Pancreas Volume Declines During the First Year After Diagnosis of Type 1 Diabetes and Exhibits Altered Diffusion at Disease Onset.Diabetes care · 2019Trial
- Trial
- Altered volume, morphology and composition of the pancreas in type 2 diabetes.PloS one · 2015 · on this mapTrial
- Pancreatic Morphological Patterns on MRI in Individuals With Suspected Type 5 Diabetes: An Exploratory Case Series From Mzuzu Central hospital, Malawi.Malawi medical journal : the journal of Medical Association of Malawi · 2026Article
- Diagnosis of chronic pancreatitis using semi-quantitative MRI features of the pancreatic parenchyma: results from the multi-institutional MINIMAP study.Abdominal radiology (New York) · 2023Article
- Article
- Review
- 3D imaging of human organs with micrometer resolution - applied to the endocrine pancreas.Communications biology · 2021Article
- Application of 3D reconstruction through CT to measure the abdominal cavity volume in the treatment of external abdominal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2021Article
- Pancreatic atrophy after gastrectomy for gastric cancer.Surgery today · 2021Article
- Article
- Healthy pancreatic parenchymal volume and its relationship to exocrine function.Pediatric radiology · 2020Article
- Cross-sectional imaging-based severity scoring of chronic pancreatitis: why it is necessary and how it can be done.Abdominal radiology (New York) · 2020Review
- Quantitative Magnetic Resonance Imaging of the Pancreas of Individuals With Diabetes.Frontiers in endocrinology · 2020Review
- Association between Pancreatic Atrophy and Loss of Insulin Secretory Capacity in Patients with Type 2 Diabetes Mellitus.Journal of diabetes research · 2019Article
- Article
- MRI quantification of pancreas motion as a function of patient setup for particle therapy -a preliminary study.Journal of applied clinical medical physics · 2016Article
- Morphology of the pancreas in type 2 diabetes: effect of weight loss with or without normalisation of insulin secretory capacity.Diabetologia · 2016Article
- MR diffusion-weighted imaging-based subcutaneous tumour volumetry in a xenografted nude mouse model using 3D Slicer: an accurate and repeatable method.Scientific reports · 2015Article
- Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo develop abdominal magnetic resonance imaging (MRI) protocol to measure pancreatic volume in humans and to validate it in large animals. MATERIALS AND
methodsWe performed abdominal MRI in eight mini-pigs using a clinical 3T MRI system. We used consecutive parallel abdominal slices, covering the entire pancreas to calculate pancreatic volume. Following MRI, animals were sacrificed, the pancreas was removed, and the volume of the pancreas was measured by water displacement. We used the same MRI protocol to measure pancreatic volume in 21 humans. To assess reproducibility of in vivo measurement we repeated MRI pancreas volume evaluation within 24 hours in additional five humans.
resultsIn mini-pigs the measurements of pancreatic volume by MRI and by water displacement were almost identical (R(2) = 0.9867; p<0.0001). In humans the average pancreas volume was 72.7+/-4.5 ml, range from 35.0 to 105.5 ml. This result is in strong agreement with results of previous large postmortem and computed tomography (CT) studies. Repeated measurements of pancreatic volume in humans were highly reproducible. Pancreatic volume measured in vivo was negatively correlated with age, body fat mass, pancreatic TG levels, and visceral fat mass.
conclusionsThese initial results are highly encouraging and our protocol for pancreatic volume estimation in vivo may prove useful in obesity research to follow in vivo changes of pancreatic volume and structure during time course of obesity and type 2 diabetes development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.