ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2013
Colorectal cancer: a researcher's perspective of the molecular angel's gone eccentric in the Vale of Kashmir.
Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Lack of association between interleukin-4 -524C>T polymorphism and colorectal cancer susceptibility.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Pooled it
- Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241Met polymorphism and gastric cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Pooled it
- SMAD7 rs12953717 polymorphism contributes to increased risk of colorectal cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Pooled it
- Article
- Genetic unraveling of colorectal cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC), being the most common cancer, is the major cause of mortality and morbidity worldwide. In Kashmir, CRC has been found to be the third most common gastrointestinal cancer after esophageal and gastric. The etiology of CRC involves two pathways: chromosomal instability (CIN) and microsatellite instability. CIN occurs in 80-85 % of CRC resulting in either gross changes in chromosome structure and number or point mutations in the chromosomes. Many molecular studies have been carried out on CRC in Kashmir so as to elucidate the role of tumor suppressor genes and oncogenes in modulating the carcinogenesis. We searched the various literature databases including Medline, PubMed, ASCO abstracts, and ESMO abstracts for the papers regarding colorectal cancer published in English using the terms "Kashmir," "colorectal cancer," "colon cancer," "rectal cancer," "carcinogenesis," "epidemiology," "genetics," "mutation," and "polymorphism." Here in this review, I have shed light on the different studies carried on CRC in our Kashmiri population in an attempt to share what we know so far about the molecular carcinogenesis of CRC in Kashmir.
Indexed as
Identifiers
23417859What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.