Evidence map›Paper›PMID 23417826›Full record

ArticleTropical animal health and production2013

Virulence profiles of enterotoxigenic, shiga toxin and enteroaggregative Escherichia coli in South African pigs.

Ramadimetja Prescilla Mohlatlole, Evelyn Madoroba, Farai Catherine Muchadeyi, Michael Chimonyo, Arnold Tapera Kanengoni, Edgar Farai Dzomba

Abstract read
PubMed Publisher
In one paragraph

Article in Tropical animal health and production, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Whole-Genome Sequencing of Human and PorcineAntibiotics (Basel, Switzerland) · 2024
    Article
  6. Article
  7. Impacts of F18Animals : an open access journal from MDPI · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Pig vaccination strategies based on enterotoxigenic Escherichia coli toxins.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Investigation of multidrug-resistant fatal colisepticaemia in weanling pigs.The Onderstepoort journal of veterinary research · 2015
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ramadimetja Prescilla MohlatloleDiscipline of Genetics, School of Life Sciences, University of KwaZulu-Natal, Private Bag X01, Scottsville, 3209, Pietermaritzburg, South Africa.
Evelyn Madoroba
Farai Catherine Muchadeyi
Michael Chimonyo
Arnold Tapera Kanengoni
Edgar Farai Dzomba
University of KwaZulu-Natal · ZAOnderstepoort Veterinary Institute · ZAAnimal Production Institute · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterotoxigenic Escherichia coli (ETEC) and shiga toxin E. coli (STEC) are important causes of colibacillosis in piglets. Recently, enteroaggregative E. coli heat-stable enterotoxin 1 (EAST-1) has been implicated in pig diarrhoea. This study investigated the prevalence of enterotoxin [heat-labile toxins (LT), heat-stable toxin a (STa), heat-stable toxin b (STb)], shiga toxins (Stx1, Stx2, Stx2e), enteroaggregative heat-stable E. coli (EAST-1), associated fimbriae (F4, F5, F6, F41, F18ab, F18ac) and non-fimbrial adhesins [adhesin involved in diffuse adherence 1 (AIDA-1), attaching and effacing factor, porcine attaching- and effacing-associated factor] in South African pigs. A total of 263 E. coli strains were isolated from Landrace (n = 24), Large White (n = 126), Duroc (n = 28) and indigenous (n = 85) breeds of piglets aged between 9 and 136 days. PCR was used in the analysis. Virulent genes were detected in 40.3% of the isolates, of which 18.6, 0.4 and 17.5% were classified as ETEC, STEC and enteroaggregative E. coli (EAEC), respectively. Individual genes were found in the following proportions: STb (19.01%), LT (0.4%), STa (3.4%), St2xe (1.1%) and EAST-1 (20.2%) toxins. None of the tested fimbriae were detected in ETEC and STEC isolates. About one third of the ETEC and STEC isolates was tested negative for both fimbrial and non-fimbrial adhesins. Twenty-five pathotypes from ETEC-, EAEC- and STEC-positive strains were identified. Pathotypes EAST-1 (30.2%), STb (13.2%) and STb/AIDA-1 (10.4%) were most prevalent. The study provided insight on possible causes of colibacillosis in South African pigs.

Indexed as

AnimalsEnterotoxigenic Escherichia coliEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFemaleFimbriae, BacterialMalePolymerase Chain ReactionPrevalenceShiga-Toxigenic Escherichia coliSouth AfricaSwineSwine DiseasesVirulence FactorsEscherichia coli ProteinsVirulence Factors

Identifiers

PMID23417826
OpenAlexW1987495274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.