ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2013
Anti-inflammatory properties of orange juice: possible favorable molecular and metabolic effects.
Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02587507 (Proteomic Analysis of the Peripheral-Blood Mononuclear Cells Response After a High-Fat, High-Carbohydrate Meal With or Without Orange Juice in Healthy Subjects), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Proteomic Analysis of the Peripheral-Blood Mononuclear Cells Response After a High-Fat, High-Carbohydrate Meal With or Without Orange Juice in Healthy Subjects
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Effects of 100% Orange Juice on Markers of Inflammation and Oxidation in Healthy and At-Risk Adult Populations: A Scoping Review, Systematic Review, and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2022Pooled it
- Dietary antioxidants, cognitive function and dementia--a systematic review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2013Pooled it
- Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals.European journal of nutrition · 2014Trial
- Orange juice with a high-fat meal prolongs postprandial lipemia in apparently healthy overweight/obese women.Archives of endocrinology and metabolismTrial
- Dietary Citrus Peel Supplementation Enhances Hepatic Energy Metabolism, Muscle 9-HODE Generation and Isoleucine Catabolism in Beef Cattle.Metabolites · 2026Article
- Effect of Hesperidin as an Adjunct to Scaling and Root Planing on Clinical Parameters and Serum C-Reactive Protein Level in Chronic Periodontitis: A Randomized, Triple-Blind, Placebo-Controlled, Clinical Trial.Journal of pharmacy & bioallied sciences · 2024Article
- Pera orange juice (Heliyon · 2024Article
- Orange juice containing Pediococcus acidilactici CE51 modulates the intestinal microbiota and reduces induced inflammation in a murine model of colitis.Scientific reports · 2023Article
- Enhanced Antioxidant Effects of Naringenin Nanoparticles Synthesized using the High-Energy Ball Milling Method.ACS omega · 2022Article
- Natural essential oil mix of sweet orange peel, cumin, and allspice elicits anti-inflammatory activity and pharmacological safety similar to non-steroidal anti-inflammatory drugs.Saudi journal of biological sciences · 2022Article
- Effect of Acute Intake of Fermented Orange Juice on Fasting and Postprandial Glucose Metabolism, Plasma Lipids and Antioxidant Status in Healthy Human.Foods (Basel, Switzerland) · 2022Article
- Drug Candidates for Autoimmune Diseases.Pharmaceuticals (Basel, Switzerland) · 2022Review
- A Combination of Mediterranean and Low-FODMAP Diets for Managing IBS Symptoms? Ask Your Gut!Microorganisms · 2022Review
- Naringenin, a citrus flavanone, enhances browning and brown adipogenesis: Role of peroxisome proliferator-activated receptor gamma.Frontiers in nutrition · 2022Article
- Influence of Consumption of Orange Juice (Citrus Sinensis) on Cardiac Remodeling of Rats Submitted to Myocardial Infarction.Arquivos brasileiros de cardiologia · 2021Article
- Novel Polymeric Biomaterial Based on Naringenin.Materials (Basel, Switzerland) · 2021Article
- Effects of High-Pressure Homogenization on Pectin Structure and Cloud Stability of Not-From-Concentrate Orange Juice.Frontiers in nutrition · 2021Article
- Hesperidin and SARS-CoV-2: New Light on the Healthy Function of Citrus Fruits.Antioxidants (Basel, Switzerland) · 2020Review
- Article
- Pulp in Shop-Bought Orange Juice Has Little Effect on Flavonoid Content and Gut Bacterial Flavanone Degradation In Vitro.Plant foods for human nutrition (Dordrecht, Netherlands) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The low-grade inflammation has been recognized as the link between adiposity and the risk of chronic metabolic disorders. Thus, increased concentrations of inflammatory markers, such as interleukins and tumor necrosis factor alpha have been found in obese individuals. In turn, diet can positively or negatively influence on the risk of chronic metabolic diseases by modulating the inflammatory status. In this context, orange juice consumption can play a role in modulation of inflammatory markers through bioactive compounds, such as the flavonoids (hesperidin, naringenin). According to this review, orange juice appears to mediate the inflammatory response in plasma level and gene expression, and in postprandial and chronic (≥7 consecutive days) periods. The current findings suggest that orange juice could be a dietary feature for prevention and treatment of chronic diseases, although more studies are necessary to evaluate the physiological and molecular mechanisms involved.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.