ReviewClinical reviews in allergy & immunology2013
Multicentric reticulohistiocytosis: a rare yet challenging disease.
Review in Clinical reviews in allergy & immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Tumor necrosis factor antagonists in the treatment of multicentric reticulohistiocytosis: Current clinical evidence.Molecular medicine reports · 2016Pooled it
- Multicentric Reticulohistiocytosis Induced Alopecia: A Clinical Case Report.Journal of cutaneous pathology · 2026Article
- Unraveling cutaneous histiocytosis: insights into histology, pathogenesis, diagnosis, and treatment pitfalls.Frontiers in medicine · 2025Review
- A case report of multicentric reticulohistiocytosis with atypical cutaneous presentation.Frontiers in immunology · 2024Article
- Multicentric reticulohistiocytosis with prominent skin lesions and arthritis: A case report.World journal of clinical cases · 2022Article
- Clinical characteristics of multicentric reticulohistiocytosis and distinguished features from rheumatoid arthritis: a single-center experience in China.Orphanet journal of rare diseases · 2022Article
- [Multicentric reticulohistiocytosis: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021Article
- The combined prevalence of classified rare rheumatic diseases is almost double that of ankylosing spondylitis.Orphanet journal of rare diseases · 2021Article
- Targetable driver mutations in multicentric reticulohistiocytosis.Haematologica · 2020Article
- The utility of FDG-PET/CT imaging in the evaluation of multicentric reticulohistiocytosis: A case report.Medicine · 2018Article
- [Rheumatoid symptoms in patients with hematologic neoplasms].Zeitschrift fur Rheumatologie · 2017Review
- Multicentric reticulohistiocytosis: case report with response to infliximab and review of treatment options.Clinical rheumatology · 2016Review
- Multicentric reticulohistiocytosis (MRH): case report with review of literature between 1991 and 2014 with in depth analysis of various treatment regimens and outcomes.SpringerPlus · 2016Review
- Organizing pneumonia associated with multicentric reticulohistiocytosis.Respirology case reports · 2015Article
- Multiple cutaneous reticulohistiocytomas successfully treated with topical psoralen plus ultraviolet A therapy combined with intralesional injections of triamcinolone acetonide.JAAD case reports · 2015Article
- The challenge of treating orphan disease.Clinical reviews in allergy & immunology · 2014Article
- Unique topics and issues in rheumatology and clinical immunology.Clinical reviews in allergy & immunology · 2014Article
- Multicentric Reticulohistiocytosis: A Case with Minimal Cutaneous Features.Indian dermatology online journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Multicentric reticulohistiocytosis (MRH) is a rare systemic inflammatory granulomatous disease that primarily manifests clinically with severe erosive arthritis and widespread papulonodular skin lesions but can involve multiple other organ systems. Despite the fact that this condition can become aggressive, debilitating as well as deforming with significant detrimental consequences, the etiology of this disease remains poorly understood. Moreover, the fact that MRH is such an uncommon disease has created an obstacle in the path of adequate clinical trials that are needed for better understanding of this phenomenon and for the development of treatment options for this patient population. In this review, we will attempt to discuss the epidemiology, pathophysiology, clinical features, associated conditions, differential diagnoses, diagnostic workup, and available treatments of MRH with the hope of creating a better understanding of this very challenging yet elusive disease process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.