ArticleParasitology research2013
Associations between innate immune function and ectoparasites in wild rodent hosts.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Macroimmunology: The drivers and consequences of spatial patterns in wildlife immune defence.The Journal of animal ecology · 2020Pooled it
- Bacterial killing assays in ecoimmunology require cross-validation by agreement statistics.Biology open · 2026Article
- Temporal variation of metacommunity structure in arthropod ectoparasites harboured by small mammals: the effects of scale and climatic fluctuations.Parasitology research · 2022Article
- Circulation of Rickettsia species and rickettsial endosymbionts among small mammals and their ectoparasites in Eastern Slovakia.Parasitology research · 2020Article
- Humane Use of Cardiac Puncture for Non-Terminal Phlebotomy of Wild-Caught and ReleasedAnimals : an open access journal from MDPI · 2020Article
- Parasite Load and Site-Specific Parasite Pressure as Determinants of Immune Indices in Two Sympatric Rodent Species.Animals : an open access journal from MDPI · 2019Article
- Variation in Local and Systemic Pro-Inflammatory Immune Markers of Wild Wood Mice after Anthelmintic Treatment.Integrative and comparative biology · 2019Article
- Risk alleles for tuberculosis infection associate with reduced immune reactivity in a wild mammalian host.Proceedings. Biological sciences · 2019Article
- Context-dependent costs and benefits of tuberculosis resistance traits in a wild mammalian host.Ecology and evolution · 2018Article
- Social and endocrine correlates of immune function in meerkats: implications for the immunocompetence handicap hypothesis.Royal Society open science · 2018Article
- Prevalence and diversity of Rickettsia species in ectoparasites collected from small rodents in Lithuania.Parasites & vectors · 2018Article
- Opposed elevational variation in prevalence and intensity of endoparasites and their vectors in a lizard.Current zoology · 2018Article
- There Is a Method to the Madness: Strategies to Study Host Complement Evasion by Lyme Disease and Relapsing Fever Spirochetes.Frontiers in microbiology · 2017Review
- First detections of Rickettsia helvetica and R. monacensis in ectoparasitic mites (Laelapidae and Trombiculidae) infesting rodents in south-western Slovakia.Parasitology research · 2015Article
- Hematologic and serum biochemical values of 4 species of Peromyscus mice and their hybrids.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014Article
- Tick community composition in Midwestern US habitats in relation to sampling method and environmental conditions.Experimental & applied acarology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immune function is an important component of host fitness, and high investment in immunity should occur when the benefits outweigh the costs, such as when risk of parasitism is high. We sampled two rodent hosts, white-footed mice (Peromyscus leucopus), and prairie voles (Microtus ochrogaster), and their tick, flea, and mite ectoparasites. A bacterial killing assay was used to measure the host's innate immune function. We hypothesized that classes of hosts (species, sexes, or age classes) with overall higher tick burdens would have a higher innate immune function as an evolutionary response to historically greater exposure. We hypothesized a weaker relationship between the fleas and mites and immune function because of high host specificity in fleas and the absence of known vector function in North American mites. Ectoparasites were significantly overdispersed on hosts. In accordance with our hypothesis, Peromyscus that had higher tick burdens also exhibited significantly higher bacterial killing ability compared to Microtus. There was no significant difference in total flea burden between rodent species and no relationship with bacterial killing ability. Microtus had higher burdens of mites in each order than Peromyscus, and female rodents had higher mite burdens than males. The benefits of maintaining high levels of innate immune factors appear to be greater than the energetic costs for Peromyscus compared to Microtus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.