Evidence map›Paper›PMID 23416942›Full record

ArticleThe Journal of cardiovascular nursing2014

Physical and psychological symptom profiling and event-free survival in adults with moderate to advanced heart failure.

Christopher S Lee, Jill M Gelow, Quin E Denfeld, James O Mudd, Donna Burgess, Jennifer K Green, Shirin O Hiatt, Corrine Y Jurgens

Abstract read
In one paragraph

Article in The Journal of cardiovascular nursing, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Which of these symptom trajectories is not like the other?European journal of cardiovascular nursing · 2024
    Article
  7. Article
  8. Survival analysis 101: an easy start guide to analysing time-to-event data.European journal of cardiovascular nursing · 2023
    Article
  9. Article
  10. Article
  11. Symptom Classes in Decompensated Liver Disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christopher S LeeChristopher S. Lee, PhD, RN, FAHA Assistant Professor, School of Nursing, Oregon Health & Science University, Portland. Jill M. Gelow, MD, MPH Assistant Professor, School of Medicine, Oregon Health & Science University, Portland. Quin E. Denfeld, BSN, RN PhD Student, School of Nursing, Oregon Health & Science University, Portland. James O. Mudd, MD Assistant Professor, School of Medicine, Oregon Health & Science University, Portland. Donna Burgess, RN, BSN Heart Failure Nurse, Oregon Health & Science University Hospital, Portland. Jennifer K. Green, MS Research Associate, School of Nursing, Oregon Health & Science University, Portland. Shirin O. Hiatt, MPH, MS, RN Research Associate, School of Nursing, Oregon Health & Science University, Portland. Corrine Y. Jurgens, PhD, RN, FAHA Associate Dean for Research, Associate Professor, School of Nursing, Stony Brook University, New York.
Jill M Gelow
Quin E Denfeld
James O Mudd
Donna Burgess
Jennifer K Green
Shirin O Hiatt
Corrine Y Jurgens
Oregon Health and Science University Hospital · USOregon Health & Science University · US

Funding

Scholars in Women's Health Research Across the LifespanK12HD043488 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI MYATT, LESLIE · 2002 to 2023
$10.4M
NICHD NIH HHS HD043488-08NICHD NIH HHS K12 HD043488NINR NIH HHS L30 NR013064
6 · The paper itself

Abstract

unlabelled: Heart failure (HF) is a heterogeneous symptomatic disorder. The goal of this study was to identify and link common profiles of physical and psychological symptoms to 1-year event-free survival in adults with moderate to advanced HF.

methodsMultiple valid, reliable, and domain-specific measures were used to assess physical and psychological symptoms. Latent class mixture modeling was used to identify distinct symptom profiles. Associations between observed symptom profiles and 1-year event-free survival were quantified using Cox proportional hazards modeling.

resultsThe mean age of the participants (n = 202) was 57 ± 13 years, 50% were men, and 60% had class III/IV HF. Three distinct profiles, mild (41.7%), moderate (30.2%), and severe (28.1%), that captured a gradient of both physical and psychological symptom burden were identified (P < .001 for all comparisons). Controlling for the Seattle HF Score, adults with the moderate symptom profile were 82% more likely (hazard ratio, 1.82; 95% confidence interval, 1.07-3.11; P = .028) and adults with the severe symptom profile were more than twice as likely (hazard ratio, 2.06; 95% confidence interval, 1.21-3.52; P = .001) to have a clinical event within 1 year than patients with the mild symptom profile.

conclusionsProfiling patterns among physical and psychological symptoms identifies HF patient subgroups with significantly worse 1-year event-free survival independent of prognostication based on objective clinical HF data.

Indexed as

Health StatusSeverity of Illness IndexAdultAgedDisease-Free SurvivalFemaleHealth BehaviorHeart FailureHumansMaleMiddle AgedPatient ComplianceRisk AssessmentSelf CareSurvival Analysis

Identifiers

PMID23416942
PMCPMC3762955
OpenAlexW2332111541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.