ReviewNature reviews. Genetics2013
Transgenerational epigenetic inheritance: how important is it?
Review in Nature reviews. Genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 102 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed.
- Influence of intergenerationalFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2017Trial
- Trial
- Obesity and Its Role in Fetal Programming-A Narrative Review.Nutrients · 2025Review
- Copper-Induced Transgenerational Plasticity in Plant Defence Boosts Aphid Fitness.Plant, cell & environment · 2025Article
- Empowering plant epigenetics to breed resilience of crops: From nucleolar dominance to transgenerational epigenetic inheritance.The plant genome · 2025Review
- Epigenetic Echoes: Bridging Nature, Nurture, and Healing Across Generations.International journal of molecular sciences · 2025Review
- Assessing Rapid Adaptation Through Epigenetic Inheritance: A New Experimental Approach.Plant, cell & environment · 2025Article
- Novel Insights into the Pathogenesis of Inflammatory Bowel Diseases.Biomedicines · 2025Review
- The RNA Revolution in the Central Molecular Biology Dogma Evolution.International journal of molecular sciences · 2024Review
- Article
- Comparison between indicine and taurine cattle DNA methylation reveals epigenetic variation associated to differences in morphological adaptive traits.Epigenetics · 2023Article
- The relative impact of parental and current environment on plant transcriptomes depends on type of stress and genotype.Proceedings. Biological sciences · 2023Article
- LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure.Cell communication and signaling : CCS · 2023Article
- Review
- Exploitation of epigenetic variation of crop wild relatives for crop improvement and agrobiodiversity preservation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- A Review on Epigenetic Inheritance of Experiences in Humans.Biochemical genetics · 2022Review
- Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models.International journal of molecular sciences · 2022Review
- Paternal diet induces transgenerational epigenetic inheritance of DNA methylation signatures and phenotypes in sheep model.PNAS nexus · 2022Article
- Epigenetic regulation of bone mass.Best practice & research. Clinical endocrinology & metabolism · 2022Review
- Wild epigenetics: insights from epigenetic studies on natural populations.Proceedings. Biological sciences · 2022Review
42 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
- Erratum issuedKelly, Bill [corrected to Kelly, William G]
Authors and funding
6 authors.
Funding
Abstract
Much attention has been given to the idea of transgenerational epigenetic inheritance, but fundamental questions remain regarding how much takes place and the impact that this might have on organisms. We asked five leading researchers in this area--working on a range of model organisms and in human disease--for their views on these topics. Their responses highlight the mixture of excitement and caution that surrounds transgenerational epigenetic inheritance and the wide gulf between species in terms of our knowledge of the mechanisms that may be involved.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.