Evidence map›Paper›PMID 23416208›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2013

Clinical characteristics and outcomes of influenza and other influenza-like illnesses in Mexico City.

Arturo Galindo-Fraga, Ana A Ortiz-Hernández, Alejandra Ramírez-Venegas, Rafael Valdez Vázquez, Sarbelio Moreno-Espinosa, Beatriz Llamosas-Gallardo, Santiago Pérez-Patrigeon, Maggie Salinger, Laura Freimanis, Chiung-yu Huang and 5 more

Abstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Systematic review on respiratory syncytial virus epidemiology in adults and the elderly in Latin America.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Pooled it
  5. Efficacy and Safety of Nitazoxanide in Addition to Standard of Care for the Treatment of Severe Acute Respiratory Illness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Arturo Galindo-FragaInstituto Nacional de Ciencias de Médicas y Nutrición Salvador Zubirán, Vasco de Quiroga 15, Col. Sección XVI, Mexico City, DF 14000, Mexico. galindofraga@yahoo.com
Ana A Ortiz-Hernández
Alejandra Ramírez-Venegas
Rafael Valdez Vázquez
Sarbelio Moreno-Espinosa
Beatriz Llamosas-Gallardo
Santiago Pérez-Patrigeon
Maggie Salinger
Laura Freimanis
Chiung-yu Huang
Wenjuan Gu
M Lourdes Guerrero
John Beigel
Guillermo M Ruiz-Palacios
La Red ILI 002 Study Group

Funding

Influenza and Emerging Infectious DiseasesZIAAI000984 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI DAVEY, RICHARD · 2009 to 2025
$44.1M
CCR NIH HHS HHSN261200800001CIntramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI000984NCI NIH HHS HHSN261200800001ENIAID NIH HHS HHSN272200900001CNIAID NIH HHS HHSN272200900031CPHS HHS HHSN27200002PHS HHS HHSN2722009000031
6 · The paper itself

Abstract

backgroundInfluenza-like illnesses (ILI) are estimated to cause millions of deaths annually. Despite this disease burden, the etiologic causes of ILI are poorly described for many geographical regions.

methodsBeginning in April 2010, we conducted an observational cohort study at five hospitals in Mexico City, enrolling subjects who met the criteria for ILI. Evaluations were conducted at enrollment and on day 28, with the collection of clinical data and a nasopharyngeal swab (or nasal aspirate in children). Swabs were tested by multiplex PCR for 15 viral pathogens and real-time PCR for influenza.

resultsDuring the first year, 1065 subjects were enrolled in this study, 55% of whom were hospitalized; 24% of all subjects were children. One or more pathogens were detected by PCR in 64% of subjects, most commonly rhinovirus (25% of all isolates) and influenza (24% of isolates). Six percent of subjects died, and of those, 54% had no pathogen identified. Rhinovirus was the most common pathogen among those who died, although it did not have the highest case fatality rate.

conclusionsMultiple respiratory viruses beyond influenza are associated with significant morbidity and mortality among adults and children in Mexico City. Detection of these agents could be useful for the adjustment of antibiotic treatment in severe cases.

Indexed as

AdolescentAdultAgedAged, 80 and overChildChild, PreschoolCohort StudiesCoronavirusCoronavirus InfectionsDiagnosis, DifferentialDNA, ViralFemaleHospitalizationHospital MortalityHumansInfantDNA, Viral

Identifiers

PMID23416208
PMCPMC3655081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.