Evidence map›Paper›PMID 23415849›Full record

ArticleDrug and alcohol dependence2013

Probability and predictors of cannabis use disorders relapse: results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

Ludwing Flórez-Salamanca, Roberto Secades-Villa, Alan J Budney, Olaya García-Rodríguez, Shuai Wang, Carlos Blanco

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models.Current topics in behavioral neurosciences · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Cannabis and mental illness: a review.European archives of psychiatry and clinical neuroscience · 2019
    Review
  15. A Model of ΔBiological psychiatry · 2018
    Article
  16. Article
  17. Evidence-based Treatment Options in Cannabis Dependency.Deutsches Arzteblatt international · 2016
    Review
  18. The natural history of substance use disorders.Current opinion in psychiatry · 2016
    Review
  19. Article
  20. Keep off the grass? Cannabis, cognition and addiction.Nature reviews. Neuroscience · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Ludwing Flórez-SalamancaDepartment of Psychiatry, New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, New York, NY 10032, United States. florezl@nyspi.columbia.edu
Roberto Secades-Villa
Alan J Budney
Olaya García-Rodríguez
Shuai Wang
Carlos Blanco
Columbia University · USDartmouth College · USNew York Psychoanalytic Society and Institute · USUniversidad de Oviedo · ES

Funding

Behavioral Treatment of Adolescent Marijuana UseR01DA015186 · NIDA · UNIV OF ARKANSAS FOR MED SCIS · PI BUDNEY, ALAN JEFFREY · 2002 to 2017
$7.7M
Towards a Comprehensive Developmental Model of Substance Use DisordersR01DA019606 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI OLFSON, MARK · 2006 to 2016
$2.6M
Development and Efficacy Test of Computerized Treatment for Marijuana DependenceR01DA023526 · NIDA · UNIV OF ARKANSAS FOR MED SCIS · PI BUDNEY, ALAN JEFFREY · 2007 to 2010
$1.6M
SMART: Improving Detection & Outcome of Psychiatric Comorbidity in Drug TreatmentR01DA020783 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI BLANCO, CARLOS · 2006 to 2010
$1.4M
Bridging Efficacy and Effectiveness in Drug Abuse TreatmentK02DA023200 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANCO, CARLOS · 2008 to 2012
$618k
Desensitization and Internalization of Mu-Opioid Receptors in the Locus CoeruleusF31DA023793 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI QUILLINAN, NIDIA · 2007 to 2008
$82k
NIDA NIH HHS DA015186NIDA NIH HHS DA020783NIDA NIH HHS DA023200NIDA NIH HHS DA023526NIDA NIH HHS DA023793NIDA NIH HHS DA19606NIDA NIH HHS F31 DA023793NIDA NIH HHS K02 DA023200NIDA NIH HHS R01 DA015186NIDA NIH HHS R01 DA019606NIDA NIH HHS R01 DA020783NIDA NIH HHS R01 DA023526
6 · The paper itself

Abstract

backgroundThis study aims to estimate the odds and predictors of Cannabis Use Disorders (CUD) relapse among individuals in remission.

methodsAnalyses were done on the subsample of individuals with lifetime history of a CUD (abuse or dependence) who were in full remission at baseline (Wave 1) of the National Epidemiological Survey of Alcohol and Related Conditions (NESARC) (n=2350). Univariate logistic regression models and hierarchical logistic regression model were implemented to estimate odds of relapse and identify predictors of relapse at 3 years follow up (Wave 2).

resultsThe relapse rate of CUD was 6.63% over an average of 3.6 year follow-up period. In the multivariable model, the odds of relapse were inversely related to time in remission, whereas having a history of conduct disorder or a major depressive disorder after Wave 1 increased the risk of relapse.

conclusionsOur findings suggest that maintenance of remission is the most common outcome for individuals in remission from a CUD. Treatment approaches may improve rates of sustained remission of individuals with CUD and conduct disorder or major depressive disorder.

Indexed as

AdolescentAdultData CollectionDiagnosis, Dual (Psychiatry)Diagnostic and Statistical Manual of Mental DisordersFemaleHealth SurveysHumansLogistic ModelsMaleMarijuana AbuseMental DisordersProbabilityPrognosisRecurrenceRiskAbuseCannabisCannabis use disorderCUDDependenceMarijuanaNESARCRelapseRemission

Identifiers

PMID23415849
PMCPMC4338368
OpenAlexW2048871519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.