Evidence map›Paper›PMID 23415829›Full record

ReviewCurrent opinion in neurobiology2013

Ominous odors: olfactory control of instinctive fear and aggression in mice.

Lisa Stowers, Peter Cameron, Jason A Keller

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Chemosensory communication of aggression: women's fine-tuned neural processing of male aggression signals.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Article
  8. An insular view of the social decision-making network.Neuroscience and biobehavioral reviews · 2019
    Review
  9. Effects of Various Cleaning Agents on the Performance of Mice in Behavioral Assays of Anxiety.Journal of the American Association for Laboratory Animal Science : JAALAS · 2018
    Article
  10. Article
  11. Article
  12. Neural deletion of Sh2b1 results in brain growth retardation and reactive aggression.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Neural map formation and sensory coding in the vomeronasal system.Cellular and molecular life sciences : CMLS · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lisa StowersThe Scripps Research Institute, Department of Molecular and Cellular Neuroscience, La Jolla, CA 92037, USA. stowers@scripps.edu
Peter Cameron
Jason A Keller

Funding

Neurosciences Graduate Training ProgramT32NS061847 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Brenda L Bloodgood · 2008 to 2026
$7.7M
Characterization of pheromone binding proteinsR01DC006885 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI STOWERS, LISA · 2004 to 2015
$4.0M
Identification of the ligands and sensory neurons that mediate pheromone behaviorR01DC009413 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI STOWERS, LISA · 2009 to 2013
$2.2M
NIDCD NIH HHS R01 DC006885NIDCD NIH HHS R01 DC009413NINDS NIH HHS T32 NS061847
6 · The paper itself

Abstract

Aggression and fear are often thought to be distinct behavioral states, yet they share several common output responses. In the mouse, both can be initiated by specialized odor cues. How these cues signal through the olfactory system to promote behavior is largely unknown. Recent experiments have started to uncover the relevant signaling ligands, chemosensory receptors, and responsive sensory neurons that together enable the precise manipulation of behaviorally relevant neural circuits. Moreover, the use of molecular genetics and new experimental strategies has begun to reveal how the central nervous system processes olfactory information to initiate aggression and fear. A sensory-initiated comparative study of these two fundamental threat reactions promises to offer new mechanistic insight.

Indexed as

OdorantsAggressionAnimalsBehavior, AnimalBrainCuesFearMiceOlfactory MucosaOlfactory PathwaysOlfactory PerceptionSmellVomeronasal Organ

Identifiers

PMID23415829
PMCPMC3661762

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.