Evidence map›Paper›PMID 23415577›Full record

SynthesisGeneral hospital psychiatry

Depression and risk of mortality in individuals with diabetes: a meta-analysis and systematic review.

Mijung Park, Wayne J Katon, Fredric M Wolf

Open access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 10 pooled it
20.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 10 syntheses or guidelines pooled it, 355 citations in OpenAlex.

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  13. Barriers to Self-Management in Depressed Women With Type 2 Diabetes.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2017
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  15. Low-income minority patient engagement with automated telephonic depression assessment and impact on health outcomes.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2015
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  16. Disruption of multisystem responses to stress in type 2 diabetes: investigating the dynamics of allostatic load.Proceedings of the National Academy of Sciences of the United States of America · 2014
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77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mijung ParkDepartment Health and Community Systems, University of Pittsburgh School of Nursing, Pittsburgh, PA 15261, USA. parkm@pitt.edu
Wayne J Katon
Fredric M Wolf
University of Washington · USUniversity of Pittsburgh · US

Funding

Training Geriatric Mental Health Services ResearchersT32MH073553 · NIMH · DARTMOUTH-HITCHCOCK CLINIC · PI BRUCE, MARTHA L · 2005 to 2019
$6.4M
Population-Based Psychiatric Intervention--Primary CareK24MH069471 · NIMH · UNIVERSITY OF WASHINGTON · PI KATON, WAYNE J · 2004 to 2011
$1.0M
NIMH NIH HHS 2 T32 MH 37553-6NIMH NIH HHS K24 MH 069471NIMH NIH HHS T32 MH073553
6 · The paper itself

Abstract

objectivesTo estimate risk of comorbid depression on all-cause mortality over time among individuals with diabetes.

methodsThe Medline, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, Embase and Science Direct databases were searched through September 30, 2012. We limited our search to longitudinal or prospective studies reporting all-cause mortality among those having depression and diabetes, compared with those having diabetes alone that used hazard ratios (HRs) as the main outcome. Two reviewers independently extracted primary data and evaluated the quality of studies using predetermined criteria. The pooled random effects adjusted HRs were estimated using meta-analysis. The impact of moderator variables on study effect size was examined with meta-regression.

resultsA total of 42,363 respondents from 10 studies were included in the analysis. Depression was significantly associated with risk of mortality (pooled HR=1.50, 95% confidence interval=1.35-1.66). Little evidence for heterogeneity was found across the studies (Cochran Q=13.52, P=.20, I(2)=26.03). No significant possibility of publication bias was detected (Egger's regression intercept=0.98, P=.23).

conclusionDepression significantly increases the risk of mortality among individuals with diabetes. Early detection and treatment of depression may improve health outcomes in this population.

Indexed as

ComorbidityDepressive DisorderDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2HumansRisk Factors

Identifiers

PMID23415577
PMCPMC3644308
OpenAlexW2109708655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.