Evidence map›Paper›PMID 23415266›Full record

ReviewClinics in perinatology2013

The altered gut microbiome and necrotizing enterocolitis.

Roberto Murgas Torrazza, Josef Neu

3 registry-linked trialsAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02573779 completednot on this mapstarted 2015, after this paper: background citation

Intestinal Microbiota and Short Term Outcomes in Very Low Birth Weight Infants Fed Primarily Donor Human Milk Compared to Infants Fed Primarily Mother's Own Milk

TypeobservationalSponsorBaylor College of MedicineRan2015 to 2018Enrolled125ConditionsInfant, Very Low Birth WeightArmsObservational - no intervention
NCT03393832 active not recruitingnot on this mapstarted 2017, after this paper: background citation

Oral Care: An Important Adjunctive Therapy to Improve Feeding Tolerance in Infants With Gastroschisis

TypeobservationalSponsorBaylor College of MedicineRan2017 to 2026Enrolled27ConditionsGastroschisis
NCT04572581 nacompletednot on this mapstarted 2020, after this paper: background citation

Use of Human Milk-Based Diet in the Late Preterm and Term Infant in the Neonatal Intensive Care Unit: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, Los AngelesRan2020 to 2022Enrolled32ConditionsBreastfeeding, Exclusive, BreastfeedingArmsDonor Breast Milk
3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Potential NICU Environmental Influences on the Neonate's Microbiome: A Systematic Review.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2015
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Necrotizing Enterocolitis and the Preterm Infant Microbiome.Advances in experimental medicine and biology · 2024
    Review
  11. Effects of prophylactic probiotics supplementation on infants born very preterm or very low birth weight.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roberto Murgas TorrazzaDivision of Neonatology, Department of Pediatrics, University of Florida College of Medicine, 1600 Southwest Archer Road, Box 100296, HD Building Room 112, Gainesville, FL 32610-0296, USA.
Josef Neu

Funding

Intestinal Microecology, Inflammatory Markers and Necrotizing EnterocolitisR01HD059143 · NICHD · UNIVERSITY OF FLORIDA · PI NEU, JOSEF · 2009 to 2013
$1.7M
NICHD NIH HHS R01 HD059143
6 · The paper itself

Abstract

Current evidence highlights the importance of developing a healthy intestinal microbiota in the neonate. Many aspects that promote health or disease are related to the homeostasis of these intestinal microbiota. Their delicate equilibrium could be strongly influenced by the intervention that physicians perform as part of the medical care of the neonate, especially preterm infants. As awareness of the importance of the development and maintenance of these intestinal flora increase and newer molecular techniques are developed, it will be possible to provide better care of infants with interventions that will have long-lasting effects.

Indexed as

Anti-Bacterial AgentsEnterocolitis, NecrotizingGenetic TechniquesHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesIntestinesMetagenomeAnti-Bacterial Agents

Identifiers

PMID23415266
PMCPMC3589666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.