ReviewClinics in perinatology2013
Lactoferrin and necrotizing enterocolitis.
Review in Clinics in perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
- Residents or Tourists: Is the Lactating Mammary Gland Colonized by Residential Microbiota?Microorganisms · 2024Review
- Factors Influencing Neonatal Gut Microbiome and Health with a Focus on Necrotizing Enterocolitis.Microorganisms · 2023Review
- The Role of Lactoferrin in Intestinal Health.Pharmaceutics · 2023Review
- Donor human milk processing and its impact on infant digestion: A systematic scoping review of in vitro and in vivo studies.Advances in nutrition (Bethesda, Md.) · 2023Article
- Lactoferrin: A glycoprotein that plays an active role in human health.Frontiers in nutrition · 2022Review
- Lactoferrin: Cytokine Modulation and Application in Clinical Practice.Journal of clinical medicine · 2021Review
- Temporal Dynamics of T Helper Populations in the Proximal Small Intestine after Oral Bovine Lactoferrin Administration in BALB/c Mice.Nutrients · 2021Article
- Children were less frequently infected with SARS-CoV-2 than adults during 2020 COVID-19 pandemic in Warsaw, Poland.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Preterm neonatal immunology at the intestinal interface.Cellular and molecular life sciences : CMLS · 2020Review
- Association between Bioactive Molecules in Breast Milk and Type 1 Diabetes Mellitus.Sultan Qaboos University medical journal · 2020Review
- Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages.Clinical and experimental immunology · 2018Article
- Mechanisms Affecting the Gut of Preterm Infants in Enteral Feeding Trials.Frontiers in nutrition · 2017Article
- The Role of Mucosal Immunity in the Pathogenesis of Necrotizing Enterocolitis.Frontiers in pediatrics · 2017Review
- Necrotizing enterocolitis: new insights into pathogenesis and mechanisms.Nature reviews. Gastroenterology & hepatology · 2016Review
- Human Milk Components Modulate Toll-Like Receptor-Mediated Inflammation.Advances in nutrition (Bethesda, Md.) · 2016Review
- Antimicrobial Proteins and Peptides in Early Life: Ontogeny and Translational Opportunities.Frontiers in immunology · 2016Review
- Human breast milk and the gastrointestinal innate immune system.Clinics in perinatology · 2014Review
- Research on neonatal microbiomes: what neonatologists need to know.Neonatology · 2014Review
- Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis.Newborn (Clarksville, Md.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Lactoferrin (LF) is a multifunctional protein and a member of the transferrin family. LF and lysozyme in breast milk kill bacteria. In the stomach, pepsin digests and releases a potent peptide antibiotic called lactoferricin from native LF. The antimicrobial characteristics of LF may facilitate a healthy intestinal microbiome. LF is the major whey in human milk; its highest concentration is in colostrum. This fact highlights early feeding of colostrum and also fresh mature milk as a way to prevent necrotizing enterocolitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.