Evidence map›Paper›PMID 23415262›Full record

ReviewClinics in perinatology2013

A clinical perspective of necrotizing enterocolitis: past, present, and future.

Renu Sharma, Mark Lawrence Hudak

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 6 pooled it
15.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed, 6 syntheses or guidelines pooled it, 234 citations in OpenAlex.

  1. Pooled it
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  16. Is necrotizing enterocolitis associated with the 896A/G polymorphism in the toll-like receptor 4 (TLR4) gene?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Article
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  18. Review
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59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Renu SharmaDivision of Neonatology, Department of Pediatrics, University of Florida College of Medicine at Jacksonville, 655 West 8th Street, Jacksonville, FL 32209, USA. renu.sharma@jax.ufl.edu
Mark Lawrence Hudak
Florida College · US

Funding

Intestinal Microecology, Inflammatory Markers and Necrotizing EnterocolitisR01HD059143 · NICHD · UNIVERSITY OF FLORIDA · PI NEU, JOSEF · 2009 to 2013
$1.7M
NICHD NIH HHS R01 HD 059143NICHD NIH HHS R01 HD059143
6 · The paper itself

Abstract

Necrotizing enterocolitis (NEC) primarily affects premature infants. It is less common in term and late preterm infants. The age of onset is inversely related to the postmenstrual age at birth. In term infants, NEC is commonly associated with congenital heart diseases. NEC has also been associated with other anomalies. More than 85% of all NEC cases occur in very low birth weight infants or in very premature infants. Despite incremental advances in our understanding of the clinical presentation and pathophysiology of NEC, universal prevention of this disease continues to elude us even in the twenty-first century.

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesAge of OnsetDisease ManagementHumansInfant, NewbornInfant, PrematureIntestinal PerforationIntestinesPneumoperitoneumPrevalenceRadiographyRisk

Identifiers

PMID23415262
PMCPMC3575605
OpenAlexW121181338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.