ArticleTheoretical biology & medical modelling2013
A clinical study of the effects of lead poisoning on the intelligence and neurobehavioral abilities of children.
Article in Theoretical biology & medical modelling, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review on the Impact of Intelligence on Cognitive Decline and Dementia Risk.Frontiers in psychiatry · 2020Pooled it
- Prospects for the Use of MICP Technology in the Remediation of Saline-Alkaline Soil Heavy Metal Pollution.Microorganisms · 2026Review
- A review of the sidelined pollutant: Reviving the fight against heavy metal contamination in an era of emerging contaminants.Toxicology reports · 2025Review
- Perspective on health and ecological risk assessments of potentially toxic metal(loid)s using aquatic biodiversity as biomonitoring indicators.Toxicology reports · 2025Review
- N-Acetylcysteine as an anti-oxidant and anti-inflammatory agent in decreasing histopathological damages and oxidative stress after mercury exposure in lung tissue of rats.BMC biotechnology · 2025Article
- Ecotoxicological health risk analysis of different fish species from the Black Sea coast of Türkiye.Scientific reports · 2025Article
- Effects of heavy metals on variation in bacterial communities in farmland soil of tailing dam collapse area.Scientific reports · 2025Article
- Environmentally Relevant Lead Exposure Alters Cell Morphology and Expression of Neural Hallmarks During SH-SY5Y Neuronal Differentiation.bioRxiv : the preprint server for biology · 2025Article
- Heavy metals: toxicity and human health effects.Archives of toxicology · 2025Review
- Prevalence and risk factors of elevated blood lead levels in 0-6-year-old children: a national cross-sectional study in China.Frontiers in public health · 2025Article
- Silica nanoparticles (SiNPs) derived from melon seed husk ameliorate Ni/Al mixture-mediated cognitive impairment in rats.Journal of medicine and life · 2024Article
- IEUBK Modeling of Children's Blood Lead Levels in Homes Served by Private Domestic Wells in Three Illinois Counties.International journal of environmental research and public health · 2024Article
- Extending Regulatory Biokinetic Lead Models towards Food Safety: Evaluation of Consumer Baby Food Contribution to Infant Blood Lead Levels and Variability.Foods (Basel, Switzerland) · 2023Article
- Complexities in attributing lead contamination to specific sources in an industrial area of Philadelphia, PA.Heliyon · 2023Article
- Exploring the invisible water insecurity of water utility shutoffs in Detroit, Michigan.GeoJournal · 2023Article
- Asymptomatic Lead Poisoning in a Pediatric Patient.Cureus · 2023Article
- Clinical and genetic characteristics of 36 children with Joubert syndrome.Frontiers in pediatrics · 2023Article
- The Butterfly Effect: Mild Soil Pollution with Heavy Metals Elicits Major Biological Consequences in Cobalt-Sensitized Broad Bean Model Plants.Antioxidants (Basel, Switzerland) · 2022Article
- Characterization of Healthy Housing in Africa: Method, Profiles, and Determinants.Journal of urban health : bulletin of the New York Academy of Medicine · 2022Article
- Assessment of Urinary Lead (Pb) and Essential Trace Elements in Autism Spectrum Disorder: a Case-Control Study Among Preschool Children in Malaysia.Biological trace element research · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLead is a heavy metal and important environmental toxicant and nerve poison that can destruction many functions of the nervous system. Lead poisoning is a medical condition caused by increased levels of lead in the body. Lead interferes with a variety of body processes and is toxic to many organs and issues, including the central nervous system. It interferes with the development of the nervous system, and is therefore particularly toxic to children, causing potentially permanent neural and cognitive impairments. In this study, we investigated the relationship between lead poisoning and the intellectual and neurobehavioral capabilities of children.
methodsThe background characteristics of the research subjects were collected by questionnaire survey. Blood lead levels were detected by differential potentiometric stripping analysis (DPSA). Intelligence was assessed using the Gesell Developmental Scale. The Achenbach Child Behavior Checklist (CBCL) was used to evaluate each child's behavior.
resultsBlood lead levels were significantly negatively correlated with the developmental quotients of adaptive behavior, gross motor performance, fine motor performance, language development, and individual social behavior (P < 0.01). Compared with healthy children, more children with lead poisoning had abnormal behaviors, especially social withdrawal, depression, and atypical body movements, aggressions and destruction.
conclusionLead poisoning has adverse effects on the behavior and mental development of 2-4-year-old children, prescribing positive and effective precautionary measures.
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