Evidence map›Paper›PMID 23414497›Full record

ArticleThe American journal on addictions

A comparison of trauma profiles among individuals with prescription opioid, nicotine, or cocaine dependence.

Katie M Lawson, Sudie E Back, Karen J Hartwell, Megan Moran-Santa Maria, Kathleen T Brady

Registry-linked trialAbstract read
In one paragraph

Article in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04760418 (Evaluating the Impact of Trauma, Trauma-Focused Therapy Services, and COVID-19 Among Patients in the University of Kentucky SMART Clinic), which is not on this map. Cited by 46 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04760418 nacompletednot on this map

Evaluating the Impact of Trauma, Trauma-Focused Therapy Services, and COVID-19 Among Patients in the University of Kentucky SMART Clinic

TypeinterventionalSponsorChristal L BadourRan2021 to 2022Enrolled21ConditionsPTSD, Opioid-use Disorder, Substance Use DisordersArmsConcurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure (COPE)
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Neural Underpinnings of Social Stress in Substance Use Disorders.Current topics in behavioral neurosciences · 2022
    Pooled it
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  7. Evaluation of coping as a mediator of the relationship between stressful life events and cancer-related distress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017
    Trial
  8. Article
  9. Article
  10. Leveraging Trauma Informed Care for Digital Health Intervention Development in Opioid Use Disorder.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
    Review
  11. Article
  12. Noninvasive Vagal Nerve Stimulation for Opioid Use Disorder.Annals of depression and anxiety · 2023
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Katie M LawsonDepartment of Human Development and Family Studies, Pennsylvania State University, State College, PA, USA. kml5509@psu.edu
Sudie E Back
Karen J Hartwell
Megan Moran-Santa Maria
Kathleen T Brady

Funding

SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE (SCTR)UL1RR029882 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$10.1M
Interdisciplinary Women's Health Research at MUSCK12HD055885 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI MCGINTY, JACQUELINE F. · 2007 to 2021
$7.2M
CLINICAL INVESTIGATION OF DRUG ABUSE DISORDERSK24DA000435 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 1999 to 2008
$1.1M
TRANSLATIONAL RESEARCH TRAINING: STRESS AND ADDICTIONK23DA021228 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2007 to 2011
$842k
PAVLOVIAN MEDIATION OF DRUG SELF-ADMINISTRATIONR01DA003608 · NIDA · OREGON HEALTH AND SCIENCE UNIVERSITY · PI CUNNINGHAM, CHRISTOPHER L · 1985 to 1991
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NCRR NIH HHS UL1 RR029882NICHD NIH HHS 5 K12 HD055885‐02NICHD NIH HHS K12 HD055885NIDA NIH HHS K23 DA021228NIDA NIH HHS K24 DA000435NIDA NIH HHS K24 DA00435NIDA NIH HHS R33 DA036085‐03
6 · The paper itself

Abstract

BACKGROUND AND

objectivesExposure to traumatic events is common among individuals with substance use disorders. Little is known, however, about the trauma histories among individuals with various types of addiction.

methodsThe present study compared the trauma histories (general, sexual, physical and emotional) of non-treatment seeking outpatients dependent on prescription opioids (n = 41), nicotine (n = 87) or cocaine (n = 73). The Life Stressor Checklist-Revised (LSC-R) was completed by participants to assess childhood and adult trauma.

resultsThe findings revealed that all three groups endorsed high levels of trauma exposure, with 96.5% of the entire sample experiencing at least one traumatic event in their lifetime. The prescription opiate group experienced a greater number of general and total traumas than the nicotine group. However, no group differences in the number of emotional, physical, or sexual traumas were revealed. The prescription opiate group reported a younger age of first traumatic event than the cocaine group, and was significantly more likely to report childhood traumatic events than both the cocaine and nicotine groups. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: The findings provide clinically relevant information that may help improve screening, interventions, and preventative efforts.

Indexed as

Life Change EventsAdultCocaine-Related DisordersFemaleHumansMaleOpioid-Related DisordersPrescription DrugsSex OffensesStress, PsychologicalTobacco Use DisorderWounds and InjuriesPrescription Drugs

Identifiers

PMID23414497
PMCPMC3681508

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.