ArticleJournal of the American Geriatrics Society2013
Health-related resource use and costs in elderly adults with and without mild cognitive impairment.
Article in Journal of the American Geriatrics Society, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Computerized cognitive training in cognitively healthy older adults: a systematic review and meta-analysis of effect modifiers.PLoS medicine · 2014Pooled it
- Effect of Music Interventions on Cognitive Function in Older Adults With Mild Cognitive Impairment: A Systematic Review.Research in gerontological nursingPooled it
- Trial
- Clinical Effectiveness of Cognitively Enhanced Tai Ji Quan Training on Global Cognition and Dual-Task Performance During Walking in Older Adults With Mild Cognitive Impairment or Self-Reported Memory Concerns : A Randomized Controlled Trial.Annals of internal medicine · 2023Trial
- Feasibility and Preliminary Efficacy of a Multimodal Approach to Increase Physical Activity in Older Adults With Memory Complaints: The Education for Action Study.Journal of aging and physical activity · 2022Trial
- Challenges with cost-utility analyses of behavioural interventions among older adults at risk for dementia.British journal of sports medicine · 2015Trial
- The impact of memory support strategies on patient recall for treatment content in individuals with and without cognitive impairment.Research square · 2026Article
- Technology Activities and Cognitive Trajectories Among Community-Dwelling Older Adults: National Health and Aging Trends Study.JMIR aging · 2025Article
- Employment, volunteering, and health-related resource use in pre-symptomatic AD: Results from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Real-world health care costs and resource utilization associated with mild cognitive impairment in the United States: A retrospective cohort study of commercial and Medicare data.Journal of managed care & specialty pharmacy · 2025Article
- The economic burden of subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia: excess costs and associated clinical and risk factors.Alzheimer's research & therapy · 2025Article
- Article
- Patterns in health care use and intensity for diagnosed and undiagnosed cognitive impairment in the older australian community: Implications for primary care management.SSM - population health · 2024Article
- Knowledge structure and future research trends of body-mind exercise for mild cognitive impairment: a bibliometric analysis.Frontiers in neurology · 2024Article
- Economic Impact of Progression from Mild Cognitive Impairment to Alzheimer Disease in the United States.The journal of prevention of Alzheimer's disease · 2024Article
- The Association of Dietary Inflammatory Index and Cognitive Function in Iranian Elders.Recent advances in food, nutrition & agriculture · 2024Article
- Healthcare costs and effects of post-COVID-19 condition in Canada.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023Article
- ADscreen: A speech processing-based screening system for automatic identification of patients with Alzheimer's disease and related dementia.Artificial intelligence in medicine · 2023Article
- Disease Burden and Progression in Patients with New-Onset Mild Cognitive Impairment and Alzheimer's Disease Identified from Japanese Claims Data: Evidence from the LIFE Study.Journal of Alzheimer's disease : JAD · 2023Article
- Medical and nursing home costs: From cognitively unimpaired through dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo assess differences in resource use and cost between older adults with and without mild cognitive impairment (MCI) over time.
designMulticenter, longitudinal study.
settingSixty-eight Alzheimer's Disease Cooperative Study (ADCS) sites in the United States.
participantsTwo hundred fifty-nine individuals diagnosed with MCI and 107 cognitively normal elderly adults followed annually for 3 years. MEASUREMENTS: The Resource Use Instrument (RUI) was used to capture medical and nonmedical care use. Generalized linear latent and mixed models were used to estimate differences in resource use and costs in older adults with and without MCI after controlling for clinical and demographic characteristics.
resultsAt baseline, average annual direct medical cost per person was substantially higher for participants with MCI ($6,499) than for those without ($2,969) P < .001). Informal care use was also substantially higher (33% vs 8.4%, P < .001). Results from multivariate analyses of longitudinal data show that, after controlling for participant and informant characteristics, direct medical costs were 44% higher for participants with MCI than for those without. Participants with MCI were almost five times as likely to use informal care as those without. Number of medical conditions and older age were associated with higher medical cost. Worse functional and cognitive status, older age, being married, and being female were associated with higher likelihood of informal care use. Having an adult child informant was associated with higher likelihood of using informal care.
conclusionThe RUI captured differences in resource use and costs between individuals with and without MCI. Clinicians who care for individuals with MCI should address informal care needs early in the disease course.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.