ArticleJRSM short reports2013
Halting the spread of epidemic pseudomonas aeruginosa in an adult cystic fibrosis centre: a prospective cohort study.
Article in JRSM short reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 7 citations in OpenAlex.
- The Effect of Strict Segregation on Pseudomonas aeruginosa in Cystic Fibrosis Patients.PloS one · 2016Trial
- Transmission, adaptation and geographical spread of theMicrobial genomics · 2021Article
- The coughing body: etiquettes, techniques, sonographies and spaces.BioSocieties · 2021Article
- Pro con debates in clinical medicine infection prevention and control in cystic fibrosis: One size fits all? The argument in favour.Paediatric respiratory reviews · 2020Review
- Infection prevention in general medical wards: A call to action.African journal of thoracic and critical care medicine · 2019Article
- Epidemiology, Biology, and Impact of Clonal Pseudomonas aeruginosa Infections in Cystic Fibrosis.Clinical microbiology reviews · 2018Review
- Risk of Bacterial Transmission in Bronchiectasis Outpatient Clinics.Current pulmonology reports · 2018Review
- Carbapenem-Resistant Non-Glucose-Fermenting Gram-Negative Bacilli: the Missing Piece to the Puzzle.Journal of clinical microbiology · 2016Review
- Development and Validation of a PCR Assay To Detect the Prairie Epidemic Strain of Pseudomonas aeruginosa from Patients with Cystic Fibrosis.Journal of clinical microbiology · 2016Article
- Infection control knowledge, beliefs and behaviours amongst cystic fibrosis patients with epidemic Pseudomonas aeruginosa.BMC pulmonary medicine · 2015Article
- Divergent, coexisting Pseudomonas aeruginosa lineages in chronic cystic fibrosis lung infections.American journal of respiratory and critical care medicine · 2015Article
- Genotypic Diversity within a Single Pseudomonas aeruginosa Strain Commonly Shared by Australian Patients with Cystic Fibrosis.PloS one · 2015Article
- A comparison of two informative SNP-based strategies for typing Pseudomonas aeruginosa isolates from patients with cystic fibrosis.BMC infectious diseases · 2014Article
- Short-sighted evolution of bacterial opportunistic pathogens with an environmental origin.Frontiers in microbiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo assess if cohort segregation policies are effective in preventing cross-infection in cystic fibrosis (CF) clinics.
designA prospective cohort study.
settingA large adult CF centre in Northwest England.
participantsAll CF patients cared for at the Liverpool adult CF centre 2003-2009.
methodsRegular sputum sampling with genotyping of pseudomonas aeruginosa (Psa) isolates led to a policy of inpatient and outpatient segregation by microbiological group.
main outcome measuresPrevalence and cross-infection/super-infection rates of a transmissible Psa strain, i.e. the Liverpool epidemic strain (LES) in adult CF patients at the Liverpool adult CF centre from 2003 to 2009.
resultsThere was a decline in the proportion of patients with LES (71-53%) and an increase in those with unique strains (23-31%) and without Psa infection (6-17%) from 2003 to 2009. There were two cases of LES super-infection and one case of new chronic Psa infection (with a unique strain). There were no cases of transmissible strain infection in patients previously uninfected by Psa.
conclusionsOur segregation policy has halted the spread of the commonest highly transmissible strain in the UK (LES) in our clinic, without endangering patients who were not previously infected with Psa. It confirms that if genotypic surveillance is used, it is unnecessary to segregate patients infected with unique strains from those without Psa infection.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.